SCHEMBL4285582

SCHEMBL4285582

COc1ccc(C(OC(C)=O)c2cccnc2OCc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.44
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
TSHR P16473 1/20 0.43
FFAR1 O14842 5/20 0.42
FAAH O00519 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ACHE P22303 1/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CNR1 P21554 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4282622 0.88 L3MBTL1 (0.47) CNR2TSHRFFAR1FAAHL3MBTL1
SCHEMBL4289336 0.85 CNR2 (0.42) CNR2PDE4APDE4BPDE4CPDE4D
SCHEMBL4279531 0.82 CYP1A2 (0.51) CNR2PDE4APDE4BPDE4CPDE4D
SCHEMBL5395059 0.75 ALDH1A1 (0.41) CNR2TSHRL3MBTL1LMNAALDH1A1
SCHEMBL4289338 0.74 LRRK2 (0.43) PDE4APDE4BPDE4CPDE4DFFAR1
SCHEMBL30741521 0.74 NPC1 (0.55) CNR2LMNAALDH1A1HTTNPSR1
SCHEMBL4285312 0.73 CNR2 (0.37) CNR2TSHRFFAR1L3MBTL1LMNA
SCHEMBL7283906 0.72 MEN1 (0.48) FFAR1L3MBTL1CA1CA2ACHE
SCHEMBL31658738 0.71 SMN1; SMN2 (0.57) CNR2FFAR1L3MBTL1LMNAALDH1A1
SCHEMBL10627201 0.71 FAAH (0.55) CNR2FAAHCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 CNR2 991/4885PDE4A 2266/4885PDE4B 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.