Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155660 | 0.92 | NAAA (0.42) | NAAADGKAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8798167 | 0.92 | NAAA (0.42) | NAAADGKAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6400340 | 0.91 | ALDH1A1 (0.35) | NAAADGKAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6155363 | 0.82 | ALDH1A1 (0.34) | NAAADGKAALDH1A1MAPTNPSR1 | |
| SCHEMBL27502960 | 0.81 | KDM4E (0.50) | NAAADGKAALDH1A1MAPTNPSR1 | |
| SCHEMBL4264982 | 0.81 | FAAH (0.45) | NAAADGKAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL15483303 | 0.81 | FAAH (0.45) | NAAADGKAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6153346 | 0.80 | ALDH1A1 (0.52) | NAAADGKAALDH1A1MAPTNPSR1 | |
| SCHEMBL16321096 | 0.80 | NAAA (0.42) | NAAADGKAALDH1A1MAPTNPSR1 | |
| SCHEMBL2695604 | 0.79 | NAAA (0.44) | NAAADGKAALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9228214-B2 | Process for the enantioselective enzymatic reduction of hydroxy keto compounds | CAMBREX IEP GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-20150152451-A1 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF HYDROXY KETO COMPOUNDS | CAMBREX IEP GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-8980592-B2 | Process for the enantioselective enzymatic reduction of hydroxy keto compounds | CAMBREX IEP GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20090221044-A1 | Process for the Enantioselective Enzymatic Reduction of Hydroxy Keto Compounds | IEP GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| WO-2008059366-A2 | PROCESS FOR THE PREPARATION OF CIS-1, 3-DIOLS FROM THE CORRESPONDING BETA-HYDROXY KETONES EMPLOYING MICROBIAL KETONE REDUCTASES | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |