SCHEMBL4286897

SCHEMBL4286897

Cc1cc(C)nc(N(C(N)=O)S(=O)(=O)c2ccccc2C(=O)O)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.43
PRSS1 P07477 3/20 0.43
PRSS2 P07478 3/20 0.43
PRSS3 P35030 3/20 0.43
KDM4E B2RXH2 2/20 0.41
FABP4 P15090 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
TSHR P16473 1/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054812 0.86 CA1 (0.50) KDM4ECA1CA2SMN1; SMN2CA9
SCHEMBL11090391 0.85 F2 (0.39) F2PRSS1PRSS2PRSS3KDM4E
SCHEMBL9352847 0.84 F2 (0.40) F2PRSS1PRSS2PRSS3FABP4
SCHEMBL27295828 0.82 KDM4E (0.56) KDM4ESMN1; SMN2TSHRMEN1KMT2A
SCHEMBL4284694 0.81 F2 (0.42) F2PRSS1PRSS2PRSS3KDM4E
SCHEMBL10800718 0.81 F2 (0.39) F2PRSS1PRSS2PRSS3KDM4E
SCHEMBL4280858 0.80 SMN1; SMN2 (0.43) F2PRSS1PRSS2PRSS3KDM4E
SCHEMBL7058406 0.79 KDM4E (0.34) KDM4ECA1CA2SMN1; SMN2CA9
SCHEMBL28412098 0.79 ALDH1A1 (0.39) KDM4ECA1CA2SMN1; SMN2TSHR
SCHEMBL1535827 0.79 F2 (0.38) F2PRSS1PRSS2PRSS3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136215-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2023-05-04 US disclosed
US-20200368302-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2020-11-26 US disclosed
CN-111357760-A Spartina alterniflora prevention and control agent and use method thereof 天津市环境保护科学研究院 2020-07-03 CN disclosed
CN-111357760-A Spartina alterniflora prevention and control agent and use method thereof 天津市环境保护科学研究院 2020-07-03 CN disclosed
US-20090259062-A1 SURFACTANT COMPOSITIONS AND ASSOCIATED METHOD MOMENTIVE PERFORMANCE MATERIALS INC. 2009-10-15 US disclosed
US-7601680-B2 Gemini silicone surfactant compositions and associated methods MOMENTIVE PERFORMANCE MATERIALS (US) 2009-10-13 US disclosed
US-20070134283-A1 Surfactant-based composition and associated methods GENERAL ELECTRIC COMPANY (US) 2007-06-14 US disclosed
US-20070135329-A1 Surfactant compositions and associated method GENERAL ELECTRIC COMPANY (US) 2007-06-14 US disclosed
EP-1136515-B1 Siloxane-containing oil compositions with good spreading properties GOLDSCHMIDT GMBH (DE) 2005-12-14 EP disclosed
US-6734141-B2 COMPRISES SILANOL-ENDCAPPED POLYETHERS FOR INCREASING RAIN-FASTNESS; HUMECTANT-FREE GOLDSCHMIDT AG (DE) 2004-05-11 US disclosed
US-4647303-A Agriculture sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-03 US disclosed
US-4627873-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-09 US disclosed
US-4592978-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-03 US disclosed
US-4591378-A Agricultural sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-27 US disclosed
US-4564384-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
US-4545808-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-08 US disclosed
US-4536576-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-20 US disclosed
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US disclosed
EP-0007687-B1 SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-30 EP disclosed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090259062-A1 SURFACTANT COMPOSITIONS AND ASSOCIATED METHOD SGMS2, SGMS1, GMNN F2 3349/4885PRSS1 1853/4885PRSS2 1848/4885
US-20070134283-A1 Surfactant-based composition and associated methods SGMS2, SGMS1, GEMIN4 F2 2420/4885PRSS1 2704/4885PRSS2 3608/4885
US-20230136215-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA F2 3324/4885PRSS1 3257/4885PRSS2 2549/4885
US-20200368302-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA F2 3324/4885PRSS1 3257/4885PRSS2 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.