Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289789 | 0.77 | NPSR1 (0.46) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL4287192 | 0.73 | MAPK1 (0.50) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL14062584 | 0.70 | ALDH1A1 (0.62) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL4645175 | 0.68 | TDP1 (0.66) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL29853739 | 0.68 | TDP1 (0.66) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL5421974 | 0.67 | L3MBTL1 (0.72) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL28982407 | 0.67 | PPARG (0.61) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL20625633 | 0.66 | TDP1 (0.49) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL28758281 | 0.66 | TDP1 (0.61) | TDP1SLC6A2SLC6A3KMT2AMAPK1 | |
| SCHEMBL501408 | 0.65 | TDP1 (0.51) | TDP1SLC6A2SLC6A3KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |