Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421974 | 0.76 | L3MBTL1 (0.72) | MAPK1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL9670389 | 0.75 | KMT2A (0.49) | NPSR1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL755285 | 0.74 | L3MBTL1 (0.51) | MAPK1NPSR1TDP1SLC6A2SLC6A3 | |
| SCHEMBL8230355 | 0.74 | RAB9A (0.51) | MAPK1NPSR1TDP1SLC6A2SLC6A3 | |
| SCHEMBL6666901 | 0.74 | L3MBTL1 (0.74) | TDP1SLC6A2SLC6A3KMT2APPARG | |
| SCHEMBL2291589 | 0.74 | L3MBTL1 (0.57) | MAPK1NPSR1TDP1SLC6A2SLC6A3 | |
| SCHEMBL4287166 | 0.73 | TDP1 (0.45) | MAPK1NPSR1TDP1SLC6A2SLC6A3 | |
| SCHEMBL5085480 | 0.73 | PPARG (0.71) | MAPK1NPSR1TDP1SLC6A2SLC6A3 | |
| SCHEMBL4288496 | 0.69 | TDP1 (0.55) | TDP1SLC6A2SLC6A3KMT2APPARG | |
| SCHEMBL28982407 | 0.69 | PPARG (0.61) | MAPK1NPSR1TDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |