Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575231 | 0.82 | LMNA (0.48) | LMNA | |
| SCHEMBL13115679 | 0.79 | ADORA2B (0.46) | ADORA2BHDAC6LMNACSNK2A2CSNK2A1 | |
| SCHEMBL2695674 | 0.76 | TRPA1 (0.64) | — | |
| SCHEMBL2695230 | 0.75 | TRPA1 (0.51) | — | |
| SCHEMBL3042764 | 0.73 | PTGS2 (0.48) | ADORA2BHDAC6CSNK2A2CSNK2A1PTGS2 | |
| SCHEMBL18704122 | 0.71 | ADORA2B (0.52) | ADORA2BHDAC6LMNACSNK2A2CSNK2A1 | |
| SCHEMBL14291770 | 0.71 | PTGS2 (0.49) | ADORA2BHDAC6LMNACSNK2A2CSNK2A1 | |
| SCHEMBL3018296 | 0.71 | ADORA2B (0.46) | ADORA2BLMNASMN1; SMN2 | |
| SCHEMBL306877 | 0.71 | STAT3 (0.47) | ADORA2BHDAC6LMNACSNK2A2CSNK2A1 | |
| SCHEMBL306478 | 0.71 | PTGS2 (0.46) | ADORA2BHDAC6LMNACSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158719-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009158719-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2009-12-30 | — | — | WO | disclosed |