SCHEMBL4288864

SCHEMBL4288864

CCc1ccc(O)c(-c2ccccc2O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.57
CNR1 P21554 2/20 0.57
CNR2 P34972 2/20 0.57
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 1/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 3/20 0.49
GAA P10253 3/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 2/20 0.49
HTT P42858 2/20 0.49
USP2 O75604 1/20 0.49
ALOX12 P18054 1/20 0.49
HPGD P15428 2/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10770170 0.90 TRPA1 (0.59) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL8047684 0.89 TRPA1 (0.70) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL29763176 0.89 TRPA1 (0.70) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL15026755 0.87 MAPT (0.53) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL12327572 0.87 TRPA1 (0.52) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL5493344 0.86 CNR1 (0.51) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL12328095 0.85 CNR1 (0.50) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL12328098 0.85 CNR1 (0.50) TRPA1CNR1CNR2ALDH1A1MAPT
SCHEMBL721719 0.85 CNR1 (0.81) CNR1CNR2ALDH1A1MAPTNPC1
SCHEMBL29154385 0.83 ALDH1A1 (0.53) TRPA1CNR1CNR2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US claimed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO claimed
WO-2002050002-A1 NON-HALOGENATED PHENYL SUBSTITUTED PHENOLS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
US-20190257049-A1 Methods and Apparatus for Stabilization of Surfaces Polylast Systems, LLC 2019-08-22 US disclosed
US-10309070-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2019-06-04 US disclosed
US-9982143-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2018-05-29 US disclosed
US-20170002533-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2017-01-05 US disclosed
US-20160333192-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2016-11-17 US disclosed
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US disclosed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO disclosed
US-7211700-B2 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same MCNEIL-PPC, INC. (US) 2007-05-01 US disclosed
US-20050239903-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same MCNEIL-PPC, INC 2005-10-27 US disclosed
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2003-11-06 US disclosed
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 TRPA1 381/4885CNR1 3523/4885CNR2 3905/4885
US-20050239903-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 TRPA1 381/4885CNR1 3523/4885CNR2 3905/4885
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 TRPA1 381/4885CNR1 3523/4885CNR2 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.