Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27952507 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 | |
| Paraben SCHEMBL4889387 | 0.91 | CA2 (0.67) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL1463186 | 0.91 | TSHR (0.64) | ALDH1A1TSHRTP53SRD5A2KDM4E | |
| Aminobenzoic Acid SCHEMBL4892404 | 0.89 | LMNA (0.56) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 | |
| 4-Methylbenzoic Acid SCHEMBL29256414 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 | |
| SCHEMBL28289613 | 0.85 | TPMT (0.48) | ALDH1A1TSHRTP53SMN1; SMN2CA2 | |
| SCHEMBL7942115 | 0.85 | KDM4E (0.56) | ALDH1A1TSHRTP53SMN1; SMN2KDM4E | |
| SCHEMBL29587539 | 0.85 | KDM4E (0.56) | ALDH1A1TSHRTP53SMN1; SMN2KDM4E | |
| SCHEMBL4289838 | 0.85 | HDAC8 (0.66) | ALDH1A1TSHRTP53ALDH2RARB | |
| Terephthalic Acid SCHEMBL27306913 | 0.84 | TSHR (0.75) | ALDH1A1TSHRTP53SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235478-A1 | ETHYLENE GLYCOL AND TEREPHTHALIC ACID RECOVERY FROM POLYETHYLENE TEREPHTHALATE DECONSTRUCTION PROCESSES | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2025-11-13 | — | — | WO | disclosed |
| CN-119775549-A | Bio-based anionic hyperdispersant and preparation method thereof | 江苏丽王科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-103597043-B | Bottom antireflective coating compositions and its method | 默克专利有限公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2718379-B1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | MERCK PATENT GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| EP-2718379-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ Electronic Materials USA Corp. (US) | 2014-04-16 | — | — | EP | disclosed |
| CN-103597043-A | Bottom antireflective coating compositions and processes thereof | AZ ELECTRONIC MATERIALS USA | 2014-02-19 | — | — | CN | disclosed |
| US-8623589-B2 | Bottom antireflective coating compositions and processes thereof | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2014-01-07 | — | — | US | disclosed |
| WO-2012168785-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-12-13 | — | — | WO | disclosed |
| US-20120308939-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-12-06 | — | — | US | disclosed |
| US-6011133-A | Laminates of glass or metal and poly(alkylene dicarboxylates) and syntheses thereof | BAYLOR UNIVERSITY (US) | 2000-01-04 | — | — | US | disclosed |
| US-5837381-A | MULTILAYER PROTECTIVE COATING; WEAR AND CORROSION RESISTANCE | UNIV BAYLOR (US) | 1998-11-17 | — | — | US | disclosed |
| US-5668224-A | TETRAALKYL- OR TRIALKYLAMMONIUM END GROUPS | BAYLOR UNIVERSITY | 1997-09-16 | — | — | US | disclosed |
| US-5451643-A | PROTECTIVE COATINGS FOR METALS OR GLASS | BAYLOR UNIVERSITY (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1994020296-A1 | POLY (ALKYLENE DICARBOXYLATES) AND SYNTHESES THEREOF | BAYLOR UNIVERSITY (US) | 1994-09-15 | — | — | WO | disclosed |