Sugi Predict

Sugi Predict / Compounds / Fluorescein

Fluorescein

Fluorescein

SCHEMBL4289974

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 8/20 0.82
▸ MAPT P10636 4/20 0.82
▸ MEN1 O00255 4/20 0.82
▸ KMT2A Q03164 4/20 0.82
▸ TDP1 Q9NUW8 3/20 0.82
▸ HTT P42858 2/20 0.82
▸ HPGD P15428 2/20 0.82
▸ RECQL P46063 2/20 0.82
▸ BLM P54132 2/20 0.82
▸ PRMT1 Q99873 2/20 0.82
▸ ACE2 Q9BYF1 2/20 0.82
▸ CYP2C19 P33261 1/20 0.82
▸ SMAD3 P84022 1/20 0.82
▸ LMNA P02545 3/20 0.59
▸ ALOX12 P18054 2/20 0.59
▸ GPR55 Q9Y2T6 2/20 0.59
▸ POLB P06746 1/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ CYP3A4 P08684 2/20 0.55
▸ ALDH1A1 P00352 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL8462127 0.92 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL21194999 0.92 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29388667 0.91 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL30272223 0.91 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL16533 0.91 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3645090 0.91 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 0.91 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL7519654 0.90 FTO (0.92) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL27157739 0.90 FTO (0.92) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL21410711 0.90 FTO (0.97) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061069-B2 Use of constrained peptide mimic oligomers as vectorization agents CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-06-23 — — US claimed
EP-3387043-B1 PROCESS FOR PREPARATION OF BIOORGANIC NYLON POLYMERS AND THEIR USE AS ANTIBACTERIAL MATERIAL UNIV MONTPELLIER (FR) 2022-09-07 — — EP disclosed
US-20220267522-A1 Process For Preparation Of Bioorganic Nylon Polymers And Their Use As Antibacterial Material UNIVERSITE DE MONTPELLIER (FR) 2022-08-25 — — US disclosed
US-11299590-B2 Process for preparation of bioorganic nylon polymers and their use as antibacterial material UNIVERSITE DE MONTPELLIER 2022-04-12 — — US disclosed
US-20210393855-A1 NEW HYDROGELS HAVING A SILYLATED STRUCTURE, AND METHOD FOR OBTAINING SAME UNIVERSITE DE MONTPELLIER (FR) 2021-12-23 — — US disclosed
US-10870925-B2 Arrays Sengenics Corporation Pte Ltd (SG) 2020-12-22 — — US disclosed
CN-111094283-A ASK 1-inhibiting pyrrolopyrimidine and pyrrolopyridine derivatives 加拉帕戈斯股份有限公司 2020-05-01 — — CN disclosed
CN-110300586-A ANTI-INFLAMMATORY COMPOSITIONS COMPRISING IRAK AND JAK INHIBITORS 加拉帕戈斯股份有限公司 2019-10-01 — — CN disclosed
CN-110088092-A Compounds, methods of obtaining compounds, pharmaceutical compositions, uses of compounds and methods of treating psychiatric and/or sleep disorders 艾奇实验室制药有限公司 2019-08-02 — — CN disclosed
US-20180305840-A1 ARRAYS Sengenics Corporation Pte Ltd (SG) 2018-10-25 — — US disclosed
WO-2008022345-A2 COMPOSITIONS AND METHODS FOR INHIBITING CYTOCHROME P450 SEQUOIA PHARMACEUTICALS, INC. (US) 2008-02-21 — — WO disclosed
CN-101031640-A Differentiation of stem cells STEM CELL INNOVATIONS INC (US) 2007-09-05 — — CN disclosed
EP-1456668-B1 PROTEIN ARRAYS FOR ALLELIC VARIANTS AND USES THEREOF SENSE PROTEOMIC LTD (GB) 2007-05-02 — — EP disclosed
EP-1742062-A2 Protein arrays for allelic variants and uses thereof SENSE PROTEOMIC LIMITED (GB) 2007-01-10 — — EP disclosed
US-20060199220-A1 Protein arrays and uses thereof BLACKBURN JONATHAN M 2006-09-07 — — US disclosed
EP-1543332-A2 PROTEIN ARRAYS AND USES THEREOF SENSE PROTEOMIC LIMITED (GB) 2005-06-22 — — EP disclosed
EP-1456668-A2 PROTEIN ARRAYS FOR ALLELIC VARIANTS AND USES THEREOF SENSE PROTEOMIC LIMITED (GB) 2004-09-15 — — EP disclosed
WO-2004025244-A2 PROTEIN ARRAYS AND USES THEREOF SENSE PROTEOMIC LIMITED (GB) 2004-03-25 — — WO disclosed
US-20040002078-A1 Arrays SENSE PROTEOMIC LIMITED 2004-01-01 — — US disclosed
WO-2003048768-A2 PROTEIN ARRAYS FOR ALLELIC VARIANTS AND USES THEREOF SENSE PROTEOMIC LIMITED (GB) 2003-06-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393855-A1 NEW HYDROGELS HAVING A SILYLATED STRUCTURE, AND METHOD FOR OBTAINING SAME ILK, CD44, VCL FTO 2325/4885MAPT 1452/4885MEN1 3985/4885
US-20220267522-A1 Process For Preparation Of Bioorganic Nylon Polymers And Their Use As Antibacterial Material DDC, PDCD2L, PCBP1 FTO 3403/4885MAPT 3384/4885MEN1 1876/4885
US-11299590-B2 Process for preparation of bioorganic nylon polymers and their use as antibacterial material DDC, PDCD2L, PCBP1 FTO 3403/4885MAPT 3384/4885MEN1 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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