Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4291831 | 0.99 | POLB (0.41) | POLBKMT2ACA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4283908 | 0.90 | KMT2A (0.53) | POLBKMT2ACA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4291345 | 0.84 | GPR88 (0.36) | POLBKMT2ACA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4752027 | 0.82 | CA1 (0.34) | POLBKMT2ACA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4294021 | 0.82 | CYP19A1 (0.34) | POLBKMT2ACA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4282906 | 0.82 | CA1 (0.34) | POLBKMT2ACA1CA2CA4 | |
| SCHEMBL4297909 | 0.78 | ALDH1A1 (0.47) | POLBKMT2ACA1CA2CA4 | |
| SCHEMBL4283151 | 0.78 | HRH4 (0.34) | POLBKMT2AHRH4HRH3DPP4 | |
| Hydrochloric Acid SCHEMBL4288220 | 0.78 | ALDH1A1 (0.46) | POLBKMT2ACA1CA2CA4 | |
| SCHEMBL4285577 | 0.75 | CA1 (0.35) | KMT2ACA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | POLB 3799/4885KMT2A 1049/4885CA1 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.