Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4288220 | 0.99 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDGLA | |
| Hydrochloric Acid SCHEMBL4282906 | 0.85 | CA1 (0.34) | KMT2APOLBGPR88CA1CA2 | |
| Hydrochloric Acid SCHEMBL4752027 | 0.85 | CA1 (0.34) | KMT2APOLBGPR88CA1CA2 | |
| Hydrochloric Acid SCHEMBL4284239 | 0.81 | L3MBTL1 (0.38) | ALDH1A1KMT2ACA1CA2CA9 | |
| SCHEMBL4292395 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDGLA | |
| SCHEMBL4293435 | 0.80 | KMT2A (0.35) | KMT2ACA1CA2CA9REN | |
| Hydrochloric Acid SCHEMBL4281746 | 0.79 | REN (0.33) | LMNAKMT2ACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL4291345 | 0.79 | GPR88 (0.36) | ALDH1A1GLAKMT2APOLBGPR88 | |
| SCHEMBL4290450 | 0.78 | POLB (0.40) | ALDH1A1KMT2APOLBGPR88CA1 | |
| Hydrochloric Acid SCHEMBL4291831 | 0.78 | POLB (0.41) | ALDH1A1KMT2APOLBGPR88CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | ALDH1A1 388/4885LMNA 1785/4885SMN1; SMN2 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.