Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291390 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTPKMNR3C2NR3C1 | |
| SCHEMBL4293593 | 0.74 | NR3C2 (0.55) | ALDH1A1MAPTNR3C2NR3C1PGR | |
| SCHEMBL4290793 | 0.74 | FNTA (0.57) | ALDH1A1MAPTPKMLMNAGAA | |
| SCHEMBL4290795 | 0.74 | FNTA (0.57) | ALDH1A1MAPTPKMLMNAGAA | |
| SCHEMBL4297353 | 0.73 | ALDH1A1 (0.71) | ALDH1A1MAPTPKMNR3C2LMNA | |
| SCHEMBL4264862 | 0.73 | ALDH1A1 (0.71) | ALDH1A1MAPTPKMNR3C2LMNA | |
| SCHEMBL707058 | 0.71 | MMP12 (0.65) | ALDH1A1NR3C2NR3C1PGR | |
| SCHEMBL5913614 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMNR3C2LMNA | |
| SCHEMBL4293294 | 0.71 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMNR3C2NR3C1 | |
| SCHEMBL352186 | 0.69 | ALDH1A1 (0.68) | ALDH1A1MAPTPKMNR3C2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1971596-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | NR3C2, NR3C1, MC2R | ALDH1A1 2708/4885MAPT 4442/4885PKM 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.