Thymol

Thymol

SCHEMBL429156

COc1cc(C)ccc1C(C)C.Cc1ccc(C(C)C)c(O)c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.72
LMNA P02545 1/20 0.72
CHRM1 P11229 1/20 0.72
SLC6A2 P23975 1/20 0.72
ADRA1A P35348 1/20 0.72
HTR2B P41595 1/20 0.72
ACHE P22303 1/20 0.47
LPAR1 Q92633 5/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymol SCHEMBL8767839 0.92 TRPA1 (0.70) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL30033430 0.89 ACHE (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL196752 0.89 ACHE (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL17629451 0.89 ACHE (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL357328 0.87 LMNA (0.88) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL429155 0.87 LMNA (0.88) TRPA1LMNACHRM1SLC6A2ADRA1A
Methoxymethane SCHEMBL901280 0.87 ACHE (0.56) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL29579824 0.85 LMNA (1.00) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL1867982 0.85 LMNA (1.00) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL30332213 0.85 LMNA (1.00) TRPA1LMNACHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2595642-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS The Procter and Gamble Company (US) 2013-05-29 EP disclosed
WO-2012012385-A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO disclosed