Methoxymethane

Methoxymethane

SCHEMBL901280

COC.COc1cc(C)ccc1C(C)C

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
TRPA1 O75762 1/20 0.50
LMNA P02545 1/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
ADRA1A P35348 1/20 0.50
HTR2B P41595 1/20 0.50
LPAR1 Q92633 4/20 0.48
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30033430 0.98 ACHE (0.58) ACHETRPA1LMNACHRM1SLC6A2
SCHEMBL17629451 0.98 ACHE (0.58) ACHETRPA1LMNACHRM1SLC6A2
SCHEMBL196752 0.98 ACHE (0.58) ACHETRPA1LMNACHRM1SLC6A2
Thymol SCHEMBL429156 0.87 TRPA1 (0.72) ACHETRPA1LMNACHRM1SLC6A2
SCHEMBL9463062 0.83 LMNA (0.54) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL11043528 0.83 LMNA (0.54) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL29527491 0.83 LMNA (0.54) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL29640497 0.83 LMNA (0.54) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL23666048 0.82 ACHE (0.54) ACHETRPA1LMNACHRM1SLC6A2
SCHEMBL20392112 0.82 LMNA (0.48) ACHETRPA1LMNACHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed