Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292670 | 1.00 | PRKCA (0.44) | PRKCAPRKCQPRKCDACACBPRKAA2 | |
| SCHEMBL4300155 | 0.95 | PRKCA (0.44) | PRKCAPRKCQPRKCDACACBPRKAA2 | |
| SCHEMBL4300154 | 0.95 | PRKCA (0.44) | PRKCAPRKCQPRKCDACACBPRKAA2 | |
| SCHEMBL7881453 | 0.91 | HRH3 (0.49) | PRKCAPRKCQPRKCDACACBUSP30 | |
| SCHEMBL4303735 | 0.91 | ACACB (0.45) | PRKCAPRKCQPRKCDACACBUSP30 | |
| SCHEMBL4303731 | 0.91 | ACACB (0.45) | PRKCAPRKCQPRKCDACACBUSP30 | |
| SCHEMBL4293266 | 0.88 | PRKCA (0.44) | PRKCAPRKCQPRKCDHRH3 | |
| SCHEMBL4297766 | 0.88 | PRKCA (0.44) | PRKCAPRKCQPRKCDHRH3 | |
| SCHEMBL4294947 | 0.88 | PRKCA (0.44) | PRKCAPRKCQPRKCDHRH3 | |
| Hydrochloric Acid SCHEMBL4290938 | 0.88 | PRKCA (0.43) | PRKCAPRKCQPRKCDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197859-A1 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders | PFIZER INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090197859-A1 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders | PFIZER INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090197859-A1 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders | PFIZER INC. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197859-A1 | Pyridinyl Amides for the Treatment of CNS and Metabolic Disorders | HTR6, HTR5A, TPH1 | PRKCA 3735/4885PRKCQ 2560/4885PRKCD 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.