SCHEMBL4292841

SCHEMBL4292841

COP(=O)(OC)c1ccccc1P(=O)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA4 P22748 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
POLB P06746 2/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CA14 Q9ULX7 1/20 0.35
NQO2 P16083 2/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3881646 0.85 TSHR (0.39) CA2CA12CA1CA4CA7
SCHEMBL29468633 0.84 HPGD (0.36) CA2CA12CA1CA4CA7
SCHEMBL777572 0.84 HPGD (0.36) CA2CA12CA1CA4CA7
SCHEMBL21319400 0.84 CA1 (0.37) CA2CA12CA1CA4CA7
SCHEMBL31306423 0.84 CYP3A4 (0.46) CA2CA12CA1CA4CA7
SCHEMBL24596898 0.84 ALDH1A1 (0.41) CA2CA12CA1CA4CA7
SCHEMBL10722239 0.84 CA1 (0.50) CA2CA12CA1CA4CA7
SCHEMBL4454668 0.82 L3MBTL1 (0.37) CA2CA12CA1CA4CA7
SCHEMBL10721636 0.80 KDM4E (0.42) POLBLMNAMEN1KMT2ATDP1
SCHEMBL16270675 0.80 CA12 (0.32) CA2CA12CA1CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293805-A Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2019-02-01 CN claimed
US-20090221530-A1 Relaxase Modulators and Methods of Using Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US claimed
US-5698022-A METAL OXIDE CHEMICAL VAPOR DEPOSITION ADVANCED TECHNOLOGY MATERIALS, INC. (US) 1997-12-16 US claimed
CN-110416621-A A method of inorganic solid electrolyte is handled using phosphorus-containing matter INST CHEMISTRY CAS 2019-11-05 CN disclosed
CN-109293805-A Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2019-02-01 CN disclosed
US-8642003-B2 Phosphine-oxide catalyzed process of production of hydrogen from silylated derivatives as hydrogen carrier UNIVERSITE D'AIX-MARSEILLE (FR) 2014-02-04 US disclosed
US-8642003-B2 Phosphine-oxide catalyzed process of production of hydrogen from silylated derivatives as hydrogen carrier UNIVERSITE D'AIX-MARSEILLE (FR) 2014-02-04 US disclosed
US-20130189183-A1 Phosphine-Oxide Catalyzed Process of Production of Hydrogen from Silylated Derivatives as Hydrogen Carrier CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-07-25 US disclosed
US-20130189183-A1 Phosphine-Oxide Catalyzed Process of Production of Hydrogen from Silylated Derivatives as Hydrogen Carrier CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-07-25 US disclosed
WO-2011098614-A1 PHOSPHINE-OXIDE CATALYZED PROCESS OF PRODUCTION OF HYDROGEN FROM SILYLATED DERIVATIVES AS HYDROGEN CARRIER UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) 2011-08-18 WO disclosed
CN-100577624-C Process for the production of acetic acid BP CHEM INT LTD 2010-01-06 CN disclosed
US-20090221530-A1 Relaxase Modulators and Methods of Using Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed
US-7256308-B2 Carbonylating methanol with an iridium carbonylation catalyst, methyl iodide, methyl acetate, water, acetic acid, a promoter of ruthenium, rhenium or osmium, and a bis-phosphonate compound BP CHEMICALS LIMITED (GB) 2007-08-14 US disclosed
WO-2007056543-A2 RELAXASE MODULATORS AND METHODS OF USING SAME THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2007-05-18 WO disclosed
CN-1659127-A Process for the preparation of acetic acid BP CHEM INT LTD (GB) 2005-08-24 CN disclosed
US-20050131251-A1 Process for the production of acetic acid BP CHEMICALS LIMITED (GB) 2005-06-16 US disclosed
EP-1509488-A1 PROCESS FOR THE PRODUCTION OF ACETIC ACID BP Chemicals Limited (GB) 2005-03-02 EP disclosed
WO-2003104179-A1 PROCESS FOR THE PRODUCTION OF ACETIC ACID BP CHEMICALS LIMITED (GB) 2003-12-18 WO disclosed
US-5698022-A METAL OXIDE CHEMICAL VAPOR DEPOSITION ADVANCED TECHNOLOGY MATERIALS, INC. (US) 1997-12-16 US disclosed
US-5698022-A METAL OXIDE CHEMICAL VAPOR DEPOSITION ADVANCED TECHNOLOGY MATERIALS, INC. (US) 1997-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131251-A1 Process for the production of acetic acid ME1, INO80C, INO80 CA2 239/4885CA12 275/4885CA1 79/4885
US-20090221530-A1 Relaxase Modulators and Methods of Using Same RXFP1, RXFP2, RXFP4 CA2 1156/4885CA12 2087/4885CA1 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.