SCHEMBL10722239

SCHEMBL10722239

COc1ccccc1P(=O)(OC)OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA14 Q9ULX7 1/20 0.50
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
CTSD P07339 1/20 0.40
MAPK1 P28482 1/20 0.40
ENPP2 Q13822 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14810055 0.85 L3MBTL1 (0.48) CA1CA2CA7CA9KMT2A
SCHEMBL4292841 0.84 CA2 (0.38) CA1CA2CA7CA9KMT2A
SCHEMBL4159719 0.82 CA1 (0.55) CA1CA2CA7CA9KMT2A
SCHEMBL30804588 0.82 CA1 (0.55) CA1CA2CA7CA9KMT2A
SCHEMBL8752544 0.80 KMT2A (0.51) CA1CA2CA7CA9KMT2A
SCHEMBL10726264 0.80 ALDH1A1 (0.44) KMT2AMEN1HTTL3MBTL1ALDH1A1
SCHEMBL30832666 0.80 CA1 (0.52) CA1CA2CA7CA9KMT2A
SCHEMBL15711836 0.80 CA1 (0.52) CA1CA2CA7CA9KMT2A
SCHEMBL3406531 0.78 PTK2B (0.58) CA1CA2CA7CA9KMT2A
SCHEMBL11412875 0.78 MEN1 (0.54) CA1CA2CA7CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127876-B1 PROCESS FOR PREPARING PHOSPHONIC-ACID ESTERS, AND PHOSPHONIC ACID DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed
US-4655883-A ANODIZING AN AROMATIC COMPOUND IN THE PRESENCE OF A PHOSPHITE AND ALKANOL IN A ELECTROLYTIC CELL HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-07 US disclosed
EP-0127876-A2 Process for preparing phosphonic-acid esters, and phosphonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-12 EP disclosed