Bronopol

Bronopol

SCHEMBL4293992

Cn1sc(Cl)cc1=O.Cn1sccc1=O.O=[N+]([O-])C(Br)(CO)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
KAT2B Q92831 10/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL14796686 0.83 KAT2B (0.39) KAT2BCA12CA1CA9
Nitric Acid SCHEMBL8587160 0.72 KAT2B (0.44) LMNAKAT2BCA12CA1CA9
Nitric Acid SCHEMBL10592665 0.70 INMT (0.39) KAT2B
SCHEMBL8427538 0.69 KAT2B (0.70) KAT2BCA12CA1CA9
Nitric Acid SCHEMBL10454247 0.69 INMT (0.38) KAT2B
SCHEMBL8576689 0.69 INMT (0.41) LMNAKAT2B
Hydrochloric Acid SCHEMBL11188349 0.68 KAT2B (0.50) KAT2BCA12CA1CA9
Calcium Chloride SCHEMBL21625034 0.67 INMT (0.45) KAT2B
Hydrochloric Acid SCHEMBL410386 0.65
Hydrochloric Acid SCHEMBL9559222 0.65 KAT2B (0.50) KAT2BCA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858387-B1 PRODUCT FOR THE TARGETED RELEASE OF TWO-COMPARTMENT ACTIVE SUBSTANCES SCS SKIN CARE SYSTEMS GMBH (DE) 2009-06-17 EP disclosed