SCHEMBL4294100

SCHEMBL4294100

C=CS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
HSD17B10 Q99714 2/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 1/20 0.59
TP53 P04637 1/20 0.59
MAPT P10636 1/20 0.59
TSHR P16473 1/20 0.59
XBP1 P17861 1/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 1/20 0.59
RAB9A P51151 1/20 0.59
MDM2 Q00987 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30697854 1.00 ALDH1A1 (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL10860893 0.87 ALDH1A1 (0.73) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL7150046 0.76 LMNA (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL7148940 0.76 NPC1 (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL1374723 0.76 ALDH1A1 (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL23320335 0.76 LMNA (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL4300190 0.76 ALDH1A1 (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL1374724 0.76 TSHR (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL11290078 0.76 ALDH1A1 (0.59) ALDH1A1HSD17B10NPC1LMNATP53
SCHEMBL2889896 0.76 TLR9 (0.67) ALDH1A1HSD17B10NPC1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184684-A Method for preparing beta-sulfonyl borate in water/organic two-phase 成都理工大学 2024-06-14 CN claimed
CN-100573999-C Nonaqueous electrolytic solution and the lithium secondary battery that comprises it SAMSUNG SDI CO LTD (KR) 2009-12-23 CN claimed
CN-100461525-C Non aqueous electrolyte and lithium secondary cell using it SAMSUNG SDI CO LTD (KR) 2009-02-11 CN claimed
CN-1532986-A Non aqueous electrolyte and lithium secondary cell using it ����SDI��ʽ���� 2004-09-29 CN claimed
CN-1531134-A Non-aqueous cell liquor and lithium secondary battery containing it 三星SDI株式会社 2004-09-22 CN claimed
US-12521453-B2 Mild and site-selective 18F-labeling of small molecules and/or biomolecules via a thiol- reactive synthon THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-13 US disclosed
CN-115057801-B F-18 marked PSMA targeted PET probe and preparation method thereof 西南医科大学附属医院 2025-01-21 CN disclosed
CN-118184684-A Method for preparing beta-sulfonyl borate in water/organic two-phase 成都理工大学 2024-06-14 CN disclosed
CN-115057801-A F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof 西南医科大学附属医院 2022-09-16 CN disclosed
US-20220072163-A1 MILD AND SITE-SELECTIVE 18F-LABELING OF SMALL MOLECULES AND/OR BIOMOLECULES VIA A THIOL-REACTIVE SYNTHON THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-10 US disclosed
EP-3817778-A1 MILD AND SITE-SELECTIVEF 18F-LABELING OF SMALL MOLECULES AND/OR BIOMOLECULES VIA A THIOL-REACTIVE SYNTHON The Regents of University of California (US) 2021-05-12 EP disclosed
US-10847841-B2 Electrolyte additive for lithium battery, organic electrolyte solution including the same, and lithium battery including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-11-24 US disclosed
CN-1532986-A Non aqueous electrolyte and lithium secondary cell using it ����SDI��ʽ���� 2004-09-29 CN disclosed
EP-0841323-B1 Method for producing arylvinylsulfone SUMITOMO CHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6399833-B1 CRYSTALLIZATION; DISSOLVING IN SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-04 US disclosed
EP-1055666-A1 PROCESS FOR PRODUCING ARYL VINYL SULFONE SOLUTION AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-11-29 EP disclosed
US-5902905-A Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-11 US disclosed
EP-0841323-A2 Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220072163-A1 MILD AND SITE-SELECTIVE 18F-LABELING OF SMALL MOLECULES AND/OR BIOMOLECULES VIA A THIOL-REACTIVE SYNTHON ALB, PTMS, GSTP1 ALDH1A1 994/4885HSD17B10 3334/4885NPC1 4206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.