SCHEMBL2889896

SCHEMBL2889896

C=CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.67
ALDH1A1 P00352 5/20 0.59
MAPT P10636 3/20 0.59
NPC1 O15118 2/20 0.59
TP53 P04637 2/20 0.59
MAPK1 P28482 2/20 0.59
RAB9A P51151 2/20 0.59
HSD17B10 Q99714 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
LMNA P02545 2/20 0.59
TSHR P16473 1/20 0.59
XBP1 P17861 1/20 0.59
HTT P42858 1/20 0.59
MDM2 Q00987 1/20 0.59
GAA P10253 3/20 0.54
TDP1 Q9NUW8 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
KMT2A Q03164 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10860893 0.87 ALDH1A1 (0.73) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL5785830 0.82 TLR9 (0.61) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL15108575 0.81 TLR9 (0.67) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL2578234 0.80 TLR9 (1.00) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL2578236 0.80 TLR9 (1.00) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL12894121 0.79 TLR9 (0.69) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL6585727 0.78 TLR9 (0.70) TLR9ALDH1A1MAPTNPC1TP53
SCHEMBL343050 0.78 TLR9 (0.70) TLR9ALDH1A1MAPTNPC1TP53
Propene SCHEMBL11202514 0.77 TDP1 (0.57) TLR9ALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL23320335 0.76 LMNA (0.59) TLR9ALDH1A1MAPTNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119936216-A Method for detecting antioxidant in jet fuel 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-118638142-A Method for preparing acyl silane by using alkene under induction of visible light 南京理工大学 2024-09-13 CN claimed
CN-118184684-A Method for preparing beta-sulfonyl borate in water/organic two-phase 成都理工大学 2024-06-14 CN claimed
CN-117486929-A Substituted alkyl germanium compound and modularized synthesis method thereof 西安交通大学 2024-02-02 CN claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
CN-1697239-A Non-aqueous electrolyte and secondary battery of lithium BIYADI CO LTD (CN) 2005-11-16 CN claimed
EP-0569484-B1 WELL CLEANOUT USING CAUSTIC ALKYL POLYGLYCOSIDE COMPOSITIONS ATLANTIC RICHFIELD CO (US) 1995-12-06 EP claimed
CN-119936216-A Method for detecting antioxidant in jet fuel 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-118638142-A Method for preparing acyl silane by using alkene under induction of visible light 南京理工大学 2024-09-13 CN disclosed
CN-118184684-A Method for preparing beta-sulfonyl borate in water/organic two-phase 成都理工大学 2024-06-14 CN disclosed
CN-117486929-A Substituted alkyl germanium compound and modularized synthesis method thereof 西安交通大学 2024-02-02 CN disclosed
US-20230322670-A1 DIPYRROLIDINE-1-ONE COMPOUNDS AND THEIR PREPARATION METHOD WUHAN JIANMIN DAPENG PHARMACEUTICAL CO., LTD. (CN) 2023-10-12 US disclosed
CN-112679469-B Tetrahydroisoquinoline derivatives, preparation method and application 山东研峰新材料科技有限公司 2021-11-16 CN disclosed
EP-0025339-A1 Microbicidal sulfones, compositions thereof and methods of preparing them UNIROYAL, INC. (US) 1981-03-18 EP disclosed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed
US-4057578-A Adducts of olefins and trichloromethane phosphonic dichloride RHONE-PROGIL (FR) 1977-11-08 US disclosed
US-4057579-A Adducts of olefins and trichloromethane phosphonic dichloride RHONE-PROGIL (FR) 1977-11-08 US disclosed
US-4021245-A GELATION DERIVATIVE, SILICIC ACID ANHYDRIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-3976672-A INSECTICIDE UNIROYAL INC. (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322670-A1 DIPYRROLIDINE-1-ONE COMPOUNDS AND THEIR PREPARATION METHOD TST, CBS, QDPR TLR9 1044/4885ALDH1A1 1818/4885MAPT 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.