Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28170249 | 0.98 | MAPK1 (0.42) | MAPK1RAB9AKDM1ASIGMAR1GNAI3 | |
| SCHEMBL23853043 | 0.87 | HRH3 (0.43) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL3412350 | 0.87 | — | — | |
| SCHEMBL3450930 | 0.85 | GNAI3 (0.43) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL3441890 | 0.84 | SIGMAR1 (0.41) | MAPK1RAB9AKDM1ASIGMAR1 | |
| SCHEMBL6659406 | 0.84 | KDM1A (0.48) | MAPK1RAB9AKDM1AGNAI3GNAO1 | |
| SCHEMBL6663102 | 0.84 | GNAI3 (0.50) | MAPK1RAB9AKDM1AGNAI3GNAO1 | |
| SCHEMBL9644931 | 0.83 | GNAI3 (0.57) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL167231 | 0.82 | PAOX (0.47) | RAB9ASIGMAR1 | |
| SCHEMBL6659172 | 0.81 | GNAI3 (0.54) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | claimed |
| EP-3707140-B1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS | COUNCIL SCIENT IND RES (IN) | 2021-10-13 | — | — | EP | claimed |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-11-05 | — | — | US | claimed |
| EP-3707140-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | Council of Scientific and Industrial Research (IN) | 2020-09-16 | — | — | EP | claimed |
| CN-118339169-A | Amine-containing vinyldisiloxane in elastomeric polymer manufacture | 盛禧奥欧洲有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115141153-B | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2023-11-14 | — | — | CN | disclosed |
| WO-2023099462-A1 | AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS | TRINSEO EUROPE GMBH (CH) | 2023-06-08 | — | — | WO | disclosed |
| EP-4186911-A1 | AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS | Trinseo Europe GmbH (CH) | 2023-05-31 | — | — | EP | disclosed |
| CN-115141153-A | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2022-10-04 | — | — | CN | disclosed |
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | disclosed |
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | disclosed |
| EP-3707140-B1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS | COUNCIL SCIENT IND RES (IN) | 2021-10-13 | — | — | EP | disclosed |
| EP-3707140-B1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS | COUNCIL SCIENT IND RES (IN) | 2021-10-13 | — | — | EP | disclosed |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-11-05 | — | — | US | disclosed |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-11-05 | — | — | US | disclosed |
| EP-3707140-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | Council of Scientific and Industrial Research (IN) | 2020-09-16 | — | — | EP | disclosed |
| US-8318769-B2 | Substituted sulfonamide compounds | GRUENETHAL GMBH (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-4272538-A | 5-Nitro-imidazole with antiprotozoic activity | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1981-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | TLR9, TLR1, TLR7 | MAPK1 109/4885RAB9A 1421/4885KDM1A 1309/4885 |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | TLR9, TLR1, TLR7 | MAPK1 128/4885RAB9A 1412/4885KDM1A 1392/4885 |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, TRPV1 | MAPK1 419/4885RAB9A 3451/4885KDM1A 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.