Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.55 |
| ▸ | AR | P10275 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | AADAC | P22760 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172449 | 0.85 | TMEM97 (0.55) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL3048651 | 0.84 | ALDH1A1 (0.59) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL25191394 | 0.84 | POLB (0.57) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL13789333 | 0.84 | TMEM97 (0.53) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL4172852 | 0.84 | TMEM97 (0.55) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL4175434 | 0.81 | TMEM97 (0.55) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL3061110 | 0.81 | AR (0.58) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL3061128 | 0.79 | AR (0.56) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL5692031 | 0.79 | AR (0.53) | TMEM97ARCYP3A4CES2ABCB11 | |
| SCHEMBL12932891 | 0.77 | AR (0.60) | TMEM97ARCYP3A4CES2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440849-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2013-05-14 | — | — | US | claimed |
| EP-2051935-B1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | ST MICROELECTRONICS SRL (IT) | 2016-09-07 | — | — | EP | disclosed |
| EP-2051935-B1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | ST MICROELECTRONICS SRL (IT) | 2016-09-07 | — | — | EP | disclosed |
| US-8766006-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-8766006-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-8766006-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2013-08-29 | — | — | US | disclosed |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2013-08-29 | — | — | US | disclosed |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2013-08-29 | — | — | US | disclosed |
| US-8440849-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-8440849-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-8440849-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2013-05-14 | — | — | US | disclosed |
| US-20090191284-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2009-07-30 | — | — | US | disclosed |
| US-20090191284-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2009-07-30 | — | — | US | disclosed |
| US-20090191284-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2009-07-30 | — | — | US | disclosed |
| EP-2051935-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMicroelectronics S.r.l. (IT) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008012845-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.L. (IT) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012845-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.L. (IT) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090191284-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | NOS2, NOS1, NOS3 | TMEM97 1759/4885AR 3453/4885CYP3A4 358/4885 |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | NOS2, NOS1, NOS3 | TMEM97 1630/4885AR 3198/4885CYP3A4 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.