Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287345 | 0.86 | RXRA (0.41) | RXRARXRBRXRGL3MBTL1CNR1 | |
| SCHEMBL4288236 | 0.79 | HTR6 (0.30) | — | |
| SCHEMBL4295097 | 0.78 | RXRA (0.36) | RXRARXRBRXRGL3MBTL1CNR1 | |
| SCHEMBL17260906 | 0.73 | FEN1 (0.41) | RXRARXRBRXRGARMRGPRX4 | |
| SCHEMBL4283825 | 0.73 | L3MBTL1 (0.47) | RXRARXRBRXRGL3MBTL1MRGPRX4 | |
| SCHEMBL23835548 | 0.71 | RXRA (0.47) | RXRARXRBRXRGL3MBTL1MRGPRX4 | |
| SCHEMBL29921217 | 0.71 | RXRA (0.47) | RXRARXRBRXRGL3MBTL1MRGPRX4 | |
| Benzyl Bromide SCHEMBL17260893 | 0.71 | FEN1 (0.39) | RXRARXRBRXRGARMRGPRX4 | |
| SCHEMBL4282756 | 0.71 | HTR6 (0.32) | AR | |
| SCHEMBL24215198 | 0.70 | L3MBTL1 (0.53) | L3MBTL1CNR1ACHECNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |