Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295539 | 0.86 | RXRA (0.38) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL4284736 | 0.79 | RXRA (0.40) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL25649981 | 0.77 | SLC22A12 (0.37) | TSHRMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4283825 | 0.76 | L3MBTL1 (0.47) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL3779104 | 0.75 | KDM4E (0.45) | TSHRALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL27347638 | 0.75 | MEN1 (0.47) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL23834854 | 0.71 | RXRA (0.47) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL29921162 | 0.71 | RXRA (0.47) | RXRARXRBRXRGMRGPRX4LMNA | |
| SCHEMBL15830708 | 0.71 | LMNA (0.36) | LMNATSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL4282756 | 0.71 | HTR6 (0.32) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |