Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299788 | 0.92 | NR3C2 (0.42) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL4287760 | 0.87 | ALDH1A1 (0.41) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL4287097 | 0.87 | ALDH1A1 (0.43) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL4296049 | 0.86 | ALDH1A1 (0.40) | MAPTALDH1A1ADRB2ADRB1GAA | |
| SCHEMBL4297388 | 0.85 | LMNA (0.45) | MAPTALDH1A1ADRB2ADRB1GAA | |
| SCHEMBL4294026 | 0.78 | ALDH1A1 (0.67) | MAPTALDH1A1GAAPKM | |
| SCHEMBL4291222 | 0.78 | NR3C2 (0.50) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL4286243 | 0.77 | NR3C2 (0.48) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL4764619 | 0.71 | NR3C2 (0.43) | NR3C2MAPTALDH1A1PGRNR3C1 | |
| SCHEMBL9909523 | 0.70 | NR3C2 (0.47) | NR3C2PGRNR3C1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253687-A1 | Fused Heterocyclic Compounds and Their Use as Mineralocorticoid Receptor Ligands | NR3C2, NR3C1, MC2R | NR3C2 1/4885MAPT 4442/4885ALDH1A1 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.