SCHEMBL429618

SCHEMBL429618

c1ccc(O[Si](Oc2ccccc2)(Oc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.43
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
KCNA3 P22001 1/20 0.36
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
KCNH2 Q12809 1/20 0.33
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
MAOA P21397 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703458 0.94 LTA4H (0.43) LTA4HTSHRCA4KDM4EGLA
SCHEMBL1482418 0.90 LTA4H (0.39) LTA4HTSHRCA4KDM4EGLA
SCHEMBL10388468 0.85 CA4 (0.44) LTA4HTSHRCA4KDM4EGLA
SCHEMBL3294871 0.85 CA4 (0.44) LTA4HTSHRCA4KDM4EGLA
SCHEMBL1482429 0.84 LTA4H (0.35) LTA4HTSHRCA4KDM4EGLA
SCHEMBL7889929 0.84 LTA4H (0.35) LTA4HTSHRCA4KDM4EGLA
SCHEMBL9173253 0.84 MAOA (0.52) TSHRKDM4EMAPTKMT2AMAOA
SCHEMBL7695708 0.84 LTA4H (0.35) LTA4HTSHRCA4KDM4EGLA
SCHEMBL3878886 0.84 ACHE (0.42) LTA4HTSHRCA4KMT2AALDH1A1
SCHEMBL3868553 0.84 LMNA (0.42) TSHRMAPTKMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
WO-2018022994-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2018-02-01 WO claimed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US claimed
EP-2665764-A2 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2013-11-27 EP claimed
WO-2012098149-A2 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2012-07-26 WO claimed
US-20120184702-A1 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2012-07-19 US claimed
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US claimed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US claimed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP claimed