Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113310 | 0.87 | KMT2A (0.40) | POLBNPSR1KMT2ANPC1MEN1 | |
| SCHEMBL164403 | 0.84 | POLB (0.49) | POLBNPSR1KMT2ANPC1MEN1 | |
| SCHEMBL18113313 | 0.84 | CYP3A4 (0.54) | NPSR1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL18113246 | 0.84 | ALDH1A1 (0.43) | POLBKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL18113214 | 0.83 | MAPT (0.46) | POLBNPSR1KMT2AALDH1A1MAPT | |
| SCHEMBL18113093 | 0.82 | PLK1 (0.43) | POLBKMT2ANPC1ALDH1A1RECQL | |
| SCHEMBL18113285 | 0.80 | RARB (0.46) | KMT2ANPC1MEN1ALDH1A1MAPT | |
| SCHEMBL6232005 | 0.78 | POLB (0.56) | POLBNPSR1KMT2ANPC1MEN1 | |
| SCHEMBL18113275 | 0.78 | ALDH1A1 (0.50) | POLBNPSR1KMT2AMEN1PIN1 | |
| SCHEMBL18113289 | 0.78 | POLB (0.46) | POLBNPSR1KMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109982719-A | Self-assembling diblock copolymers comprised of PEGMEMA and drug-loaded polymer segments | RS研究教育咨询医学工业贸易股份有限公司 | 2019-07-05 | — | — | CN | disclosed |
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| US-7615661-B2 | Thioester compounds and their use in fragrance or flavor applications | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615661-B2 | Thioester compounds and their use in fragrance or flavor applications | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615661-B2 | Thioester compounds and their use in fragrance or flavor applications | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-20090232747-A1 | THIOESTER COMPOUNDS AND THEIR USE IN FRAGRANCE OR FLAVOR APPLICATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-09-17 | — | — | US | disclosed |
| US-20090232747-A1 | THIOESTER COMPOUNDS AND THEIR USE IN FRAGRANCE OR FLAVOR APPLICATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-09-17 | — | — | US | disclosed |
| US-20090232747-A1 | THIOESTER COMPOUNDS AND THEIR USE IN FRAGRANCE OR FLAVOR APPLICATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232747-A1 | THIOESTER COMPOUNDS AND THEIR USE IN FRAGRANCE OR FLAVOR APPLICATIONS | ACOT7, PPT1, LYPLA1 | POLB 4406/4885NPSR1 2222/4885KMT2A 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.