SCHEMBL4298281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL443532	0.89	DGAT1 (0.52)	DGAT1NPC1ALDH1A1POLBSMN1; SMN2
	SCHEMBL16691194	0.89	DGAT1 (0.55)	DGAT1NPC1ALDH1A1POLBSMN1; SMN2
	SCHEMBL4298343	0.88	DGAT1 (0.67)	DGAT1NPC1ALDH1A1RAB9A
	SCHEMBL4296607	0.88	DGAT1 (0.68)	DGAT1KLKB1NOTUM
	SCHEMBL4486967	0.88	DGAT1 (0.52)	DGAT1NPC1ALDH1A1POLBSMN1; SMN2
	SCHEMBL408172	0.87	NPSR1 (0.60)	DGAT1NPC1ALDH1A1POLBSMN1; SMN2
	SCHEMBL4299394	0.82	DGAT1 (0.61)	DGAT1NPC1ALDH1A1MAPK1NPSR1
	SCHEMBL408173	0.81	NPC1 (0.45)	DGAT1NPC1MAPK1NPSR1RAB9A
	SCHEMBL4300650	0.81	NPSR1 (0.59)	DGAT1NPC1ALDH1A1SMN1; SMN2MAPK1
	SCHEMBL19795577	0.81	JUN (0.50)	DGAT1NPC1ALDH1A1MAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.