Oxaloacetate

Oxaloacetate

SCHEMBL6545256

N.O=C(O)CC(=O)C(=O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.53
SRR Q9GZT4 1/20 0.53
OR51E2 Q9H255 3/20 0.47
EGLN1 Q9GZT9 2/20 0.47
MAPK1 P28482 1/20 0.47
SLC13A3 Q8WWT9 1/20 0.47
FEN1 P39748 6/20 0.40
ERCC5 P28715 5/20 0.40
PTPN1 P18031 2/20 0.40
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
HAO1 Q9UJM8 3/20 0.37
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
FFAR3 O14843 1/20 0.33
GLRA1 P23415 1/20 0.33
SLC6A9 P48067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxaloacetate SCHEMBL6545252 1.00 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8464 0.96
Oxaloacetate SCHEMBL4298763 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL898612 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL25210523 0.93
Oxaloacetate SCHEMBL8638879 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9994505 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9782818 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL20912993 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL11328361 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105603015-B A kind of production method of L-glufosinate-ammonium 浙江大学 2018-12-11 CN disclosed
CN-108893455-A A kind of transaminase mutant and its application for producing L-glufosinate-ammonium 浙江工业大学 2018-11-27 CN disclosed
US-9783840-B2 Decalcification solution with preservation of RNA JACQUET ROBIN DIFEO (US) 2017-10-10 US disclosed
CN-107119084-A A kind of method that utilization transaminase and ethylene synthetase produce L glufosinate-ammoniums 浙江大学 2017-09-01 CN disclosed
US-20160289743-A1 DECALCIFICATION SOLUTION WITH PRESERVATION OF RNA THE UNIVERSITY OF AKRON (US) 2016-10-06 US disclosed
US-9383297-B2 Decalcification solution with preservation of RNA THE UNIVERSITY OF AKRON (US) 2016-07-05 US disclosed
US-20040170598-A1 Polysaccharide -polypeptide polymer; antiinflammatory agents, immunomoderators; culture product; applying stresses; anticancer agents; aids therapy GRANADA BIO TECH, S.A. DE C.V. (MX) 2004-09-02 US disclosed
EP-1373540-A1 POLYSUBSTITUTED POLYCARBOXYLIC PHOSPHOAMIDE BIOPOLYMERS, METHODS FOR THEIR PRODUCTION AND USES OF COMPOSITIONS DERIVED THEREFROM Granada Bio Tech SA DE CV (MX) 2004-01-02 EP disclosed
CN-1415760-A Transfer related gene ACADEMY OF TAIWAN UNIV (CN) 2003-05-07 CN disclosed
WO-2002081720-A1 POLYSUBSTITUTED POLYCARBOXYLIC PHOSPHOAMIDE BIOPOLYMERS, METHODS FOR THEIR PRODUCTION AND USES OF COMPOSITIONS DERIVED THEREFROM GRANADA BIO TECH SA DE CV (MX) 2002-10-17 WO disclosed
US-4267268-A Spermatozoa extenders OLD STONE BANK, A RHODE ISLAND BANKING CORP. 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170598-A1 Polysaccharide -polypeptide polymer; antiinflammatory agents, immunomoderators; culture product; applying stresses; anticancer agents; aids therapy PGAM1, PGM2, PGAM5 LDHA 763/4885SRR 2975/4885OR51E2 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.