Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427394 | 0.76 | SLC22A2 (0.43) | TAAR1RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5331811 | 0.73 | CHKA (0.56) | RAB9AALDH1A1LMNACHKAHTT | |
| Iodide SCHEMBL7437383 | 0.72 | CHKA (0.55) | RAB9AALDH1A1LMNACHKAHTT | |
| Bromide SCHEMBL15140537 | 0.72 | CHKA (0.58) | RAB9AALDH1A1LMNACHKAHTT | |
| Hydrochloric Acid SCHEMBL7441129 | 0.72 | ALDH1A1 (0.56) | RAB9AALDH1A1LMNACHKAHTT | |
| SCHEMBL5328940 | 0.69 | RAB9A (0.47) | RAB9ANPC1ALDH1A1LMNAHTT | |
| SCHEMBL5823234 | 0.69 | IDO1 (0.35) | RAB9ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8427192 | 0.68 | CHKA (0.44) | RAB9AALDH1A1LMNACHKAHTT | |
| SCHEMBL8429196 | 0.68 | PABPC1 (0.50) | RAB9AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13527278 | 0.67 | MEN1 (0.50) | RAB9ANPC1LMNACHKAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009533384-A | — | — | 2009-09-17 | — | — | JP | claimed |
| US-20090093443-A1 | COMBINATIONS OF 4- BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JASSEN PHARMACEUTICA N.V. (BE) | 2009-04-09 | — | — | US | claimed |
| EP-2009991-A1 | COMBINATIONS OF 4-BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007116051-A1 | COMBINATIONS OF 4-BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-18 | — | — | WO | claimed |
| WO-2006087356-A2 | SYNERGISTIC ANTIFOULING COMPOSITIONS COMPRISING (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-24 | — | — | WO | claimed |
| US-5958900-A | Use of organoboron compounds as antifouling agents | AMERICAN CYANAMID COMPANY (US) | 1999-09-28 | — | — | US | claimed |
| WO-1997042823-A1 | USE OF ORGANOBORON COMPOUNDS AS ANTIFOULING AGENTS | AMERICAN CYANAMID COMPANY (US) | 1997-11-20 | — | — | WO | claimed |
| US-5354740-A | For phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | claimed |
| CN-101420851-B | Combination of 4-bromo-2- (4-chlorophenyl) -5- (trifluoromethyl) -1H-pyrrole-3-carbonitrile and biocidal compound | JANSSEN PHARMACEUTICA NV | 2013-08-07 | — | — | CN | disclosed |
| CN-101420851-A | Combination of 4-bromo-2- (4-chlorophenyl) -5- (trifluoromethyl) -1H-pyrrole-3-carbonitrile and biocidal compound | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-29 | — | — | CN | disclosed |
| US-20090093443-A1 | COMBINATIONS OF 4- BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JASSEN PHARMACEUTICA N.V. (BE) | 2009-04-09 | — | — | US | disclosed |
| US-20090093443-A1 | COMBINATIONS OF 4- BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JASSEN PHARMACEUTICA N.V. (BE) | 2009-04-09 | — | — | US | disclosed |
| EP-2009991-A1 | COMBINATIONS OF 4-BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-07 | — | — | EP | disclosed |
| EP-2009991-A1 | COMBINATIONS OF 4-BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-07 | — | — | EP | disclosed |
| JP-2004244395-A | (4-ISOPROPYLPYRIDINIO)METHYLDIPHENYLBORON-CONTAINING COMPOSITION HAVING IMPROVED STABILITY | K I CHEMICAL INDUSTRY CO LTD | 2004-09-02 | — | — | JP | disclosed |
| US-5958900-A | Use of organoboron compounds as antifouling agents | AMERICAN CYANAMID COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0624315-B1 | Diaryl(pyridinio and isoquinolinio) boron fungicidal agents | AMERICAN CYANAMID CO (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997042823-A1 | USE OF ORGANOBORON COMPOUNDS AS ANTIFOULING AGENTS | AMERICAN CYANAMID COMPANY (US) | 1997-11-20 | — | — | WO | disclosed |
| EP-0624315-A1 | Diaryl(pyridinio and isoquinolinio) boron fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5354740-A | For phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093443-A1 | COMBINATIONS OF 4- BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND BIOCIDAL COMPOUNDS | TET3, TPM4, TET1 | CNR2 863/4885TAAR1 3473/4885ORAI1 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.