SCHEMBL429978

SCHEMBL429978

Cc1cccc2ccc(B3OC(C)(C)C(C)(C)O3)cc12

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 11/20 0.53
LPL P06858 10/20 0.53
CYP1A2 P05177 3/20 0.49
CYP2A6 P11509 2/20 0.49
IRAK4 Q9NWZ3 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
EGFR P00533 1/20 0.40
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
CSF1R P07333 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL429987 0.87 LIPG (0.49) LIPGLPLCYP1A2CYP2A6IRAK4
SCHEMBL1643598 0.84 LIPG (0.53) LIPGLPLIRAK4EGFRIDO1
SCHEMBL2358141 0.84 LIPG (0.53) LIPGLPLIRAK4EGFRIDO1
SCHEMBL29444278 0.83 LPL (0.59) LIPGLPLCYP1A2CYP2A6IRAK4
SCHEMBL2453344 0.83 LPL (0.59) LIPGLPLCYP1A2CYP2A6IRAK4
SCHEMBL28706226 0.83 LIPG (0.51) LIPGLPLCYP1A2IRAK4EGFR
SCHEMBL12877280 0.83 LIPG (0.51) LIPGLPLCYP1A2CYP2A6IRAK4
SCHEMBL29341518 0.83 LIPG (0.51) LIPGLPLIRAK4ALDH1A1HPGD
SCHEMBL15424089 0.82 LPL (0.46) LIPGLPLIRAK4EGFRIDO1
SCHEMBL1629562 0.81 LPL (0.51) LIPGLPLIRAK4IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
US-8084937-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2011-12-27 US disclosed
US-8084937-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2011-12-27 US disclosed
EP-2045231-B1 Binaphthyl compound and organic light emitting element using the same CANON KK (JP) 2010-07-21 EP disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
EP-2045231-A1 Binaphthyl compound and organic light emitting element using the same Canon Kabushiki Kaisha (JP) 2009-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME ALPL, MT-ND4L, LAGE3 LIPG 2208/4885LPL 1254/4885CYP1A2 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.