Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503443 | 0.88 | CASP6 (0.62) | CASP6TPMTTSHRLMNAALDH1A1 | |
| SCHEMBL11560452 | 0.88 | AKR1C3 (0.50) | CASP6TPMTTSHRLMNAGPR35 | |
| 3,5-Dinitrosalicylic Acid SCHEMBL11870749 | 0.85 | GPR35 (0.53) | CASP6TPMTLMNAALDH1A1GPR35 | |
| SCHEMBL644782 | 0.83 | TTR (0.63) | CASP6TPMTTSHRLMNAALDH1A1 | |
| SCHEMBL30606818 | 0.83 | TTR (0.63) | CASP6TPMTTSHRLMNAALDH1A1 | |
| 3,5-Dinitrosalicylic Acid SCHEMBL29350581 | 0.81 | ALDH1A1 (0.61) | TSHRLMNAALDH1A1GPR35MAPT | |
| 3,5-Dinitrosalicylic Acid SCHEMBL28323234 | 0.81 | ALDH1A1 (0.61) | TSHRLMNAALDH1A1GPR35MAPT | |
| 3,5-Dinitrosalicylic Acid SCHEMBL125292 | 0.81 | ALDH1A1 (0.61) | TSHRLMNAALDH1A1GPR35MAPT | |
| SCHEMBL16714067 | 0.81 | CASP6 (0.55) | CASP6TPMTTSHRLMNAALDH1A1 | |
| SCHEMBL5110264 | 0.80 | AKR1C4 (0.56) | LMNAALDH1A1GPR35POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582719-B1 | Carboxylic-acid-terminated hyperbranched poly(benzoxazole) and the star block copolymers therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-09-01 | — | — | US | disclosed |