Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 8/20 | 0.63 |
| ▸ | TPMT | P51580 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | COMT | P21964 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30606818 | 1.00 | TTR (0.63) | TTRTPMTGPR35ABCC3ABCC4 | |
| SCHEMBL16098896 | 0.92 | TTR (0.59) | TTRTPMTGPR35ABCC3ABCC4 | |
| SCHEMBL503443 | 0.90 | CASP6 (0.62) | TTRTPMTGPR35ALDH1A1LMNA | |
| SCHEMBL7368380 | 0.86 | TTR (0.81) | TTRGPR35ABCC3ABCC4NR1I2 | |
| SCHEMBL3768831 | 0.85 | TTR (0.55) | TTRTPMTGPR35KDM4EALDH1A1 | |
| SCHEMBL7375755 | 0.85 | TTR (0.59) | TTRGPR35ABCC3ABCC4NR1I2 | |
| SCHEMBL8726192 | 0.85 | TTR (0.59) | TTRGPR35ABCC3ABCC4NR1I2 | |
| Bromide SCHEMBL7365276 | 0.85 | TTR (0.78) | TTRGPR35ABCC3ABCC4NR1I2 | |
| SCHEMBL6036460 | 0.83 | TTR (0.62) | TTRGPR35ABCC3ABCC4NR1I2 | |
| SCHEMBL8731833 | 0.83 | TTR (0.61) | TTRGPR35ABCC3ABCC4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003404-A | High ammonia nitrogen wastewater treatment reagent | 苏州森荣环保处置有限公司 | 2023-11-07 | — | — | CN | claimed |
| US-9642810-B2 | Formulation containing carbidopa, levodopa, and entacapone | MYLAN INC. (US) | 2017-05-09 | — | — | US | claimed |
| US-20160022589-A1 | FORMULATION CONTAINING CARBIDOPA, LEVODOPA, AND ENTACAPONE | MYLAN INC. | 2016-01-28 | — | — | US | claimed |
| WO-2014151742-A1 | FORMULATION CONTAINING CARBIDOPA, LEVODOPA, AND ENTACAPONE | MYLAN, INC. (US) | 2014-09-25 | — | — | WO | claimed |
| WO-2014147464-A2 | NOVEL PROCESS FOR THE PREPARATION OF TOLCAPONE | RA CHEM PHARMA LIMITED (IN) | 2014-09-25 | — | — | WO | claimed |
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
| CN-117003404-A | High ammonia nitrogen wastewater treatment reagent | 苏州森荣环保处置有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | US | disclosed |
| EP-3917933-A1 | DUOCARMYCIN ANALOGUES | Auckland Uniservices Limited (NZ) | 2021-12-08 | — | — | EP | disclosed |
| CN-113439084-A | Duocarmycin analogs | 奥克兰联合服务有限公司 | 2021-09-24 | — | — | CN | disclosed |
| WO-2020157662-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-08-06 | — | — | WO | disclosed |
| US-9642810-B2 | Formulation containing carbidopa, levodopa, and entacapone | MYLAN INC. (US) | 2017-05-09 | — | — | US | disclosed |
| CN-1170405-A | Aryl and heteroaryl sulfonamide derivatives, their preparation and their use as endothelin antagonists | HOFFMANN LA ROCHE (CH) | 1998-01-14 | — | — | CN | disclosed |
| US-5705703-A | ENZYME INHIBITORS OF TRANSFERASES | HOFFMANN-LA ROCHE INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5633371-A | ENZYME INHIBITORS; TREATMENT OF DEPRESSION AND PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5476875-A | Catechol derivatives | HOFFMAN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5389653-A | Inhibitors of the enzyme catechol-O-methyltransferase; useful as co-medication in treatment of Parkinson's disease | HOFFMAN-LA ROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5236952-A | Inhibit the enzyme catechol-O-methyltransferase; for treatment of Parkinson's disease administered with L-dopa | HOFFMANN-LA ROCHE INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0237929-B1 | 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| EP-0237929-A1 | 3,5-Disubstituted pyrocatechol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | TTR 655/4885TPMT 589/4885GPR35 977/4885 |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | TOP2A, TOP2B, MUS81 | TTR 4882/4885TPMT 164/4885GPR35 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.