Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4304761 | 0.99 | AKR1C3 (0.42) | AKR1C3AKR1C2FFAR1PPARAKDM4E | |
| SCHEMBL609392 | 0.91 | KDM4E (0.53) | AKR1C3AKR1C2FFAR1PPARAKDM4E | |
| Hydrochloric Acid SCHEMBL4310601 | 0.84 | FFAR1 (0.45) | AKR1C3AKR1C2FFAR1PPARAKDM4E | |
| SCHEMBL11937520 | 0.81 | KDM4E (0.43) | FFAR1PPARAKDM4EPPARDUSP2 | |
| SCHEMBL14346892 | 0.80 | FFAR1 (0.49) | AKR1C3AKR1C2FFAR1PPARAKDM4E | |
| SCHEMBL608498 | 0.79 | KDM4C (0.53) | FFAR1PPARAKDM4EALDH1A1RORC | |
| SCHEMBL11929758 | 0.78 | CFD (0.56) | AKR1C3AKR1C2FFAR1KDM4EALDH1A1 | |
| SCHEMBL4116154 | 0.78 | KDM4C (0.52) | FFAR1PPARAKDM4EALDH1A1RORC | |
| SCHEMBL4299252 | 0.75 | KDM4C (0.37) | AKR1C3AKR1C2FFAR1PPARAKDM4E | |
| Sulfuric Acid SCHEMBL1170031 | 0.75 | PPARA (0.49) | FFAR1PPARAKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | claimed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | claimed |
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | S.H. PHARMA., LTD. (KR) | 2011-03-10 | — | — | US | disclosed |
| WO-2009108017-A2 | NEW PYRUVATE DERIVATIVES WITH NEUROPROTECTIVE EFFECT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | S.H. PHARMA., LTD (KR) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060156-A1 | Pyruvate Derivatives with Neuroprotective Effect, Process for Preparing the Same and Pharmaceutical Composition Comprising the Same | PC, PDK1, PDK2 | AKR1C3 367/4885AKR1C2 281/4885FFAR1 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.