SCHEMBL609392

SCHEMBL609392

CC(=O)Oc1ccc(NCCc2ccc(C(F)(F)F)cc2)cc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.53
▸ USP2 O75604 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ CFD P00746 2/20 0.52
▸ AKR1C3 P42330 1/20 0.45
▸ AKR1C2 P52895 1/20 0.45
▸ BACE1 P56817 1/20 0.44
▸ FFAR1 O14842 1/20 0.44
▸ PPARA Q07869 4/20 0.44
▸ PPARD Q03181 1/20 0.44
▸ RORC P51449 2/20 0.43
▸ CNR1 P21554 1/20 0.42
▸ CCR5 P51681 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ BCL2A1 Q16548 1/20 0.42
▸ PLAAT3 P53816 1/20 0.40
▸ PLAAT5 Q96KN8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4300412 0.91 AKR1C3 (0.43) KDM4EUSP2ALDH1A1HPGDCYP2C19
Hydrochloric Acid SCHEMBL4304761 0.90 AKR1C3 (0.42) KDM4EUSP2ALDH1A1HPGDCYP2C19
SCHEMBL11937520 0.90 KDM4E (0.43) KDM4EUSP2ALDH1A1HPGDCYP2C19
SCHEMBL11929758 0.87 CFD (0.56) KDM4EALDH1A1HPGDHSD17B10CFD
Hydrochloric Acid SCHEMBL4310601 0.86 FFAR1 (0.45) KDM4EAKR1C3AKR1C2FFAR1PPARA
SCHEMBL8231707 0.83 RORC (0.43) KDM4EUSP2ALDH1A1HPGDCYP2C19
Methoxymethane SCHEMBL5321026 0.83 KDM4E (0.49) KDM4EUSP2ALDH1A1HPGDCYP2C19
SCHEMBL14346892 0.82 FFAR1 (0.49) KDM4EAKR1C3AKR1C2FFAR1PPARA
SCHEMBL608498 0.81 KDM4C (0.53) KDM4EALDH1A1FFAR1PPARARORC
Methoxymethane SCHEMBL5318080 0.81 CCR5 (0.51) KDM4EALDH1A1HSD17B10CFDAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902536-B1 COMPOSITIONS COMPRISING 5-BENZYLAMINOSALICYLIC ACID COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IN A COMPANION ANIMAL GNT PHARMA CO LTD (KR) 2025-09-03 — — EP claimed
EP-4456890-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT Pharma Co., Ltd (KR) 2024-11-06 — — EP claimed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 — — WO claimed
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-07-27 — — US claimed
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2022-08-04 — — US claimed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 — — CN claimed
CN-113710242-A Compositions and methods for treating neurodegenerative disorders 吉恩特药业株式会社 2021-11-26 — — CN claimed
EP-3902536-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT Pharma Co., Ltd (KR) 2021-11-03 — — EP claimed
WO-2020136441-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2020-07-02 — — WO claimed
US-20200206172-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2020-07-02 — — US claimed
EP-2394645-B1 Medical use of 5-benzylamino salicylic acid derivatives or salts thereof NEUROTECH PHARMACEUTICALS CO LTD (KR) 2014-10-08 — — EP claimed
US-8598383-B2 Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2013-12-03 — — US claimed
US-20130316988-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2013-11-28 — — US claimed
US-8455470-B2 Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases NEUROTECH PHARMACEUTICALS CO., LTD (KR) 2013-06-04 — — US claimed
US-20120209025-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases GWAG BYOUNG-JOO (KR) 2012-08-16 — — US claimed
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2012-02-16 — — US claimed
US-20090281181-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases GNT PHARMA CO., LTD. (KR) 2009-11-12 — — US claimed
US-20090240079-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2009-09-24 — — US claimed
EP-2004164-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES Neurotech Co., Ltd. (KR) 2008-12-24 — — EP claimed
WO-2007119973-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE AND INFLAMMATORY DISEASES NEUROTECH CO., LTD. (KR) 2007-10-25 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS HAO2, ACOX1, HAO1 KDM4E 3173/4885USP2 2315/4885ALDH1A1 309/4885
US-20120209025-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B KDM4E 4368/4885USP2 2082/4885ALDH1A1 446/4885
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS PRNP, PSEN1, GRIK5 KDM4E 2064/4885USP2 1850/4885ALDH1A1 859/4885
US-20090240079-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B KDM4E 4368/4885USP2 2082/4885ALDH1A1 446/4885
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT HTR5A, HTR6, MC5R KDM4E 1632/4885USP2 3619/4885ALDH1A1 133/4885
US-20090281181-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B KDM4E 4368/4885USP2 2082/4885ALDH1A1 446/4885
US-20130316988-A1 Pharmaceutical Composition for Treating or Preventing Degenerative and Inflammatory Diseases ALOX12, ALOX15, ALOX15B KDM4E 4368/4885USP2 2082/4885ALDH1A1 446/4885
US-20200206172-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS PRNP, PSEN1, GRIK5 KDM4E 2064/4885USP2 1850/4885ALDH1A1 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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