Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366242 | 0.74 | DDB1 (0.44) | DDB1CRBNGRM5ADORA1ADORA2A | |
| SCHEMBL14007394 | 0.73 | SMN1; SMN2 (0.48) | DDB1CRBNGRM5MEN1KMT2A | |
| SCHEMBL12247671 | 0.70 | GRM5 (0.49) | DDB1CRBNGRM5ADORA1ADORA2A | |
| SCHEMBL3824076 | 0.68 | NPC1 (0.44) | DDB1CRBNGRM5ADORA1ADORA2A | |
| SCHEMBL2378788 | 0.67 | GRM5 (0.43) | DDB1CRBNGRM5ADORA1ALDH1A1 | |
| SCHEMBL27997348 | 0.67 | GRM5 (0.43) | DDB1CRBNGRM5ALDH1A1KDM4E | |
| SCHEMBL11856799 | 0.67 | GRM5 (0.43) | DDB1CRBNGRM5ADORA1MEN1 | |
| SCHEMBL5377724 | 0.65 | GRM5 (0.41) | DDB1CRBNGRM5MEN1KMT2A | |
| SCHEMBL21668017 | 0.65 | GRM5 (0.41) | DDB1CRBNGRM5ALDH1A1KDM4E | |
| SCHEMBL5374700 | 0.65 | GRM5 (0.41) | DDB1CRBNGRM5EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156398-A1 | Fungicidal 5-alkyl-6-phenylpyrazolopyrimidin-7-ylamines | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20080221130-A1 | Fungicidal 5-Methyl-6-Phenylpyrazolopyrimidin-7-Ylamines | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221130-A1 | Fungicidal 5-Methyl-6-Phenylpyrazolopyrimidin-7-Ylamines | CYP3A7, CYP51A1, PNMT | DDB1 2551/4885CRBN 1255/4885GRM5 663/4885 |
| US-20090156398-A1 | Fungicidal 5-alkyl-6-phenylpyrazolopyrimidin-7-ylamines | CYP3A7, CYP51A1, ERG28 | DDB1 3393/4885CRBN 1062/4885GRM5 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.