Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515622 | 0.85 | PTGS2 (0.30) | — | |
| SCHEMBL1654108 | 0.85 | ALDH1A1 (0.31) | — | |
| SCHEMBL24516002 | 0.77 | LMNA (0.38) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL19468425 | 0.73 | NQO2 (0.36) | KDM4E | |
| SCHEMBL431297 | 0.69 | GRIN2D (0.34) | KDM4E | |
| SCHEMBL24515872 | 0.64 | EDNRA (0.39) | POLB | |
| SCHEMBL24516546 | 0.63 | CES2 (0.38) | — | |
| SCHEMBL1408550 | 0.62 | — | — | |
| SCHEMBL7208069 | 0.62 | — | — | |
| SCHEMBL5599027 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185564-B1 | Herbicidally active cyclopentanedione compounds and derivatives thereof | SYNGENTA LTD (GB) | 2014-06-18 | — | — | EP | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| EP-2429979-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010057880-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057880-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-05-27 | — | — | WO | disclosed |
| EP-2185564-A2 | TRICYCLIC BRIDGED CYCLOPENTANEDIONE DERIVATIVES AS HERBICIDES | Syngenta Limited (GB) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009019005-A2 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | TAS1R3 1987/4885TAS1R1 1426/4885TAS1R2 1720/4885 |
| US-20120094832-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | TAS1R3 1829/4885TAS1R1 1143/4885TAS1R2 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.