Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093479 | 0.85 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4551977 | 0.84 | HRH1 (0.42) | CYP4F2CYP4A11ALDH1A1HPGD | |
| SCHEMBL4300107 | 0.84 | HRH1 (0.42) | CYP4F2CYP4A11ALDH1A1HPGD | |
| SCHEMBL4106475 | 0.81 | PTGER4 (0.34) | PTGER4PTGER2PTGER3 | |
| SCHEMBL4300961 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2211707 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL4254643 | 0.73 | CYP4A11 (0.58) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4080955 | 0.73 | PTGER4 (0.39) | CYP4F2CYP4A11LMNAPTGER4PTGER2 | |
| SCHEMBL3980166 | 0.73 | PTGER4 (0.39) | CYP4F2CYP4A11LMNAPTGER4PTGER2 | |
| SCHEMBL4305398 | 0.73 | FKBP1A (0.33) | ALDH1A1LMNAHPGDTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270395-A1 | EP4 Receptor Agonist, Compositions and Methods Thereof | MERCK & CO., INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090270395-A1 | EP4 Receptor Agonist, Compositions and Methods Thereof | MERCK & CO., INC. | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270395-A1 | EP4 Receptor Agonist, Compositions and Methods Thereof | PTGER4, PTGER1, PTGER3 | CYP4F2 1044/4885CYP4A11 90/4885ALDH1A1 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.