Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302439 | 1.00 | MAPT (0.61) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094257 | 0.85 | MAPT (0.63) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094183 | 0.84 | MAPT (0.73) | MAPTALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL4302445 | 0.82 | OGG1 (0.45) | MAPTALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL23094206 | 0.78 | ALDH1A1 (0.79) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094214 | 0.77 | MAPT (0.71) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094200 | 0.77 | LMNA (0.74) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094192 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094204 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL23094216 | 0.75 | TDP1 (0.67) | MAPTALDH1A1GAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |