Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302442 | 0.82 | MAPT (0.61) | LMNAMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4302439 | 0.82 | MAPT (0.61) | LMNAMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL23094183 | 0.68 | MAPT (0.73) | LMNAMAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL29626821 | 0.67 | ALDH1A1 (0.62) | LMNAMAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL23094257 | 0.67 | MAPT (0.63) | LMNAMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL198282 | 0.67 | ALDH1A1 (0.62) | LMNAMAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL21467760 | 0.66 | HPGD (0.56) | MAPTSMN1; SMN2KMT2APOLBHPGD | |
| SCHEMBL15892681 | 0.66 | CTSD (0.61) | LMNAMAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL5730768 | 0.66 | CA2 (0.59) | LMNAMAPTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL1033641 | 0.66 | LMNA (0.61) | LMNAMAPTSMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |