SCHEMBL430264

SCHEMBL430264

CC(Cl)(OP(=O)(OC(C)(Cl)C(Cl)Cl)OC(C)(Cl)C(Cl)Cl)C(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430265 0.80 LMNA (0.32) CYP2C19LMNA
SCHEMBL537766 0.71 THRB (0.32)
SCHEMBL8853322 0.71 THRB (0.32)
SCHEMBL207305 0.68 CYP2C19 (0.30) CYP2C19LMNA
SCHEMBL11080915 0.67 TSHR (0.33)
SCHEMBL919508 0.67
SCHEMBL7045716 0.67
SCHEMBL11598998 0.67
SCHEMBL11710151 0.66
SCHEMBL486485 0.64 TSHR (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693805-A Polyurethane sealing material and preparation method and application thereof 广东汉石新材料科技有限公司 2023-09-05 CN claimed
CN-111793459-B Novel flame-retardant low-shrinkage polyurethane foam joint mixture 安徽南大星新材料科技有限公司 2023-03-28 CN claimed
CN-213593859-U Movable plastic ground for amusement park 付晓龙 2021-07-02 CN claimed
CN-213286772-U Trichloroisopropyl phosphate preparation is with hydrolysis tank 浙江万盛股份有限公司 2021-05-28 CN claimed
CN-111793459-A Novel flame-retardant low-shrinkage polyurethane foam joint mixture 安徽南大星新材料科技有限公司 2020-10-20 CN claimed
EP-1401930-B2 NON-COMBUSTIBLE POLYESTERPOLYOL AND/OR POLYETHERPOLYOL PREBLEND FOR PRODUCING FOAMED PRODUCTS SOLVAY FLUOR GMBH (DE) 2017-02-22 EP claimed
EP-1401930-B1 NON-COMBUSTIBLE POLYESTERPOLYOL AND/OR POLYETHERPOLYOL PREBLEND FOR PRODUCING FOAMED PRODUCTS SOLVAY FLUOR GMBH (DE) 2008-12-17 EP claimed
US-20040149955-A1 Non-combustible polyesterpolyol and/or polyetherpolyol preblend for producing foamed products SOLVAY FLUOR UND DERIVATE GMBH (DE) 2004-08-05 US claimed
EP-0766713-B1 FOAMING AGENTS CONTAINING LIQUID CARBON DIOXIDE SOLVAY FLUOR & DERIVATE (DE) 1998-04-08 EP claimed
EP-3458491-B1 PROCESS FOR PREPARING POLYISOCYANURATE RIGID FOAMS BASF SE (DE) 2026-03-25 EP disclosed
EP-3717243-B1 POLYURETHANE-BASED INSULATION BOARD DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-26 EP disclosed
US-12378179-B2 Process for production of an alkoxylated product BAKELITE GMBH (DE) 2025-08-05 US disclosed
EP-2350178-B2 METHOD FOR PRODUCING A FLAME RETARDANT FOAM FORMING COMPOSITION SOUDAL (BE) 2025-04-23 EP disclosed
WO-2025009991-A1 IRREVERSIBLE TEMPERATURE INDICATOR LABEL ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ТЕРМОЭЛЕКТРИКА" 2025-01-09 WO disclosed
US-4826623-A Homogeneous microemulsion compositions based on halogenated polyhydroxylated compounds and halogenated alkanes and their application to the manufacture of rigid foams ATOCHEM (FR) 1989-05-02 US disclosed
EP-0177381-B1 HOMOGENEOUS COMPOSITIONS ON THE BASIS OF HALOGENATED POLYHYDROXY COMPOUNDS AND HALOGENATED ALKANES; THEIR USE IN THE PREPARATION OF RIGID FOAMS ELF ATOCHEM S.A. (FR) 1989-02-08 EP disclosed
US-4742087-A MOISTURE HARDENING HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-05-03 US disclosed
EP-0177381-A1 Homogeneous compositions on the basis of halogenated polyhydroxy compounds and halogenated alkanes; their use in the preparation of rigid foams ELF ATOCHEM S.A. (FR) 1986-04-09 EP disclosed
US-4128532-A Polyetheresters which contain hydroxyl groups and the use thereof in the production of flame resistant synthetic resins BAYER AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4046742-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378179-B2 Process for production of an alkoxylated product ALKBH3, PUF60, PFAS CYP2C19 192/4885LMNA 1974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.