Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 7/20 | 0.38 |
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303999 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CCR2BTKEPHX1MMP2 | |
| SCHEMBL2307409 | 0.90 | CCR2 (0.40) | ALDH1A1CCR2MMP2ANPEPNR1H2 | |
| SCHEMBL29389706 | 0.90 | CCR2 (0.40) | ALDH1A1CCR2MMP2ANPEPNR1H2 | |
| SCHEMBL2307831 | 0.90 | CCR2 (0.40) | ALDH1A1CCR2MMP2ANPEPNR1H2 | |
| SCHEMBL2306832 | 0.89 | CCR2 (0.44) | ALDH1A1CCR2MMP2ANPEPNR1H2 | |
| SCHEMBL1266962 | 0.89 | CCR2 (0.44) | ALDH1A1CCR2MMP2ANPEPNR1H2 | |
| SCHEMBL4311053 | 0.88 | BTK (0.48) | CCR2BTKEPHX1MMP2ANPEP | |
| SCHEMBL4311050 | 0.88 | BTK (0.48) | CCR2BTKEPHX1MMP2ANPEP | |
| SCHEMBL4311057 | 0.88 | BTK (0.48) | CCR2BTKEPHX1MMP2ANPEP | |
| SCHEMBL2309467 | 0.88 | CCR2 (0.45) | ALDH1A1CCR2MMP2ANPEPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069376-A1 | VLA-4 Antagonists | MERCK SHARP & DOHME CORP. | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069376-A1 | VLA-4 Antagonists | VCAM1, SELPLG, ITGB4 | ALDH1A1 854/4885CCR2 529/4885BTK 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.