Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979840 | 0.77 | ALDH1A1 (0.48) | SOD1LMNAKMT2AADRA2ACYP2D6 | |
| SCHEMBL3064663 | 0.71 | FFAR1 (0.54) | SOD1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL19982393 | 0.71 | ALDH1A1 (0.46) | SOD1LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL3979841 | 0.69 | CYP1A2 (0.47) | SOD1KMT2ACYP2D6MEN1CYP3A4 | |
| SCHEMBL3454803 | 0.67 | ALDH1A1 (0.51) | SOD1LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL3408304 | 0.66 | KMT2A (0.42) | LMNAKMT2AADRA2ACYP2D6HIF1A | |
| SCHEMBL10388336 | 0.66 | TEAD1 (0.59) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8552122 | 0.66 | SOD1 (0.37) | SOD1LMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL14290971 | 0.64 | ALDH1A1 (0.36) | SOD1LMNAKMT2AMEN1HTR2A | |
| SCHEMBL8469629 | 0.64 | TSHR (0.39) | SOD1KMT2AMEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127722-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |