Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487951 | 0.87 | TLR8 (0.44) | CYP1A2TLR8ESR1ESR2HSD17B1 | |
| SCHEMBL30487941 | 0.87 | TLR8 (0.44) | CYP1A2TLR8ESR1ESR2HSD17B1 | |
| SCHEMBL10714677 | 0.86 | CYP1A2 (0.52) | CYP1A2GABRA1GABRB2CYP3A4FAAH | |
| SCHEMBL4302061 | 0.85 | MCL1 (0.53) | CYP1A2GABRA1GABRB2CYP3A4FAAH | |
| SCHEMBL10224689 | 0.82 | TSHR (0.50) | CYP1A2TSHRTLR8ESR1ESR2 | |
| SCHEMBL27904877 | 0.82 | CLK1 (0.44) | CYP1A2TLR8ANPEPDPP4ESR1 | |
| SCHEMBL28325207 | 0.81 | AKR1B1 (0.46) | PTGS1TLR8MEN1KMT2ACLK1 | |
| SCHEMBL11745542 | 0.79 | GABRA1 (0.48) | CYP1A2GABRA1GABRB2CYP3A4FAAH | |
| SCHEMBL19604459 | 0.79 | TLR8 (0.41) | CYP1A2SLC6A2TLR8ESR1ESR2 | |
| SCHEMBL8781801 | 0.78 | UGT2B7 (0.42) | CYP1A2GABRA1GABRB2CYP3A4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969272-B2 | Hydroxyaromatic functionalized polyalpha-olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-03-03 | — | — | US | claimed |
| US-20210094919-A1 | KRAS MUTANT PROTEIN INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. | 2021-04-01 | — | — | US | disclosed |
| US-8969272-B2 | Hydroxyaromatic functionalized polyalpha-olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8946188-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-01-23 | — | — | US | disclosed |
| US-8461128-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-11 | — | — | US | disclosed |
| WO-2009131765-A1 | HYDROXYAROMATIC FUNCTIONALIZED POLYALPHA-OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090270296-A1 | HydroxyAromatic Functionalized Polyalpha-Olefins | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-02 | — | — | US | disclosed |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-02 | — | — | US | disclosed |
| EP-0701577-B1 | POLYMER ALKYLATION OF HYDROXYAROMATIC COMPOUNDS | EXXON CHEMICAL PATENTS INC (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0701577-A1 | POLYMER ALKYLATION OF HYDROXYAROMATIC COMPOUNDS | EXXON CHEMICAL PATENTS INC. (US) | 1996-03-20 | — | — | EP | disclosed |
| CN-1031188-C | Process for producing hydroxy group-containing alkyl aromatic compound | SUMITOMO CHEMICAL CO (JP) | 1996-03-06 | — | — | CN | disclosed |
| EP-0249415-B2 | Production of alkylated hydroxy aromatic compounds | SUMITOMO CHEMICAL CO (JP) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994028035-A1 | POLYMER ALKYLATION OF HYDROXYAROMATIC COMPOUNDS | EXXON CHEMICAL PATENTS INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| US-5334775-A | Reacting with a terminally unsaturated polymer in the presence of a partially or completely dehydrated heteropoly catalyst; precursors for production of fuel and lubricant additives | EXXON CHEMICAL PATENTS INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-RE34076-E | Alkylation catalysis of aromatic alcohol with alkylating agent in presence of heteropoly acid and water | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| US-4912264-A | Liquid phase alkylation of a hydroxyl containing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-27 | — | — | US | disclosed |
| CN-87104109-A | Process for producing hydroxy group-containing alkyl aromatic compound | — | 1988-01-20 | — | — | CN | disclosed |
| EP-0249415-A2 | Production of alkylated hydroxy aromatic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | CYP1A2 4485/4885GABRA1 3823/4885GABRB2 4243/4885 |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | CYP1A2 4485/4885GABRA1 3823/4885GABRB2 4243/4885 |
| US-20210094919-A1 | KRAS MUTANT PROTEIN INHIBITORS | KRAS, NRAS, APC | CYP1A2 4406/4885GABRA1 4163/4885GABRB2 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.