Butenone

Butenone

SCHEMBL490740

CC(=O)C=Cc1ccccc1.CC(=O)C=Cc1ccccc1.[Pd]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.95
GLA P06280 1/20 0.95
MAPT P10636 4/20 0.64
LMNA P02545 3/20 0.64
ALDH1A1 P00352 3/20 0.64
HDAC3 O15379 2/20 0.64
HDAC4 P56524 2/20 0.64
HDAC1 Q13547 2/20 0.64
HDAC2 Q92769 2/20 0.64
HDAC8 Q9BY41 2/20 0.64
HDAC6 Q9UBN7 2/20 0.64
PLIN1 O60240 2/20 0.64
RECQL P46063 2/20 0.64
PLIN5 Q00G26 2/20 0.64
ABHD5 Q8WTS1 2/20 0.64
F3 P13726 2/20 0.64
TNKS O95271 1/20 0.64
HCAR2 Q8TDS4 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC10 Q969S8 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butenone SCHEMBL792625 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL2891566 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL5788285 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL699144 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL29739250 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL4306181 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL7053850 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL6401376 1.00 TDP1 (0.95) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL12984182 0.98 TDP1 (1.00) TDP1GLAMAPTLMNAALDH1A1
Butenone SCHEMBL76632 0.98 TDP1 (1.00) TDP1GLAMAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409614-A Difluoromethyl heteroarene compound and preparation method thereof 国网安徽省电力有限公司电力科学研究院 2025-02-11 CN claimed
CN-117534620-A Preparation method of palladium-catalyzed hydrocarbon bond functionalized 2-trifluoromethyl benzimidazole compound 六盘水师范学院 2024-02-09 CN claimed
US-20020170730-A1 Electromagnetic shielding plate and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-11-21 US claimed
EP-1239717-A2 Electromagnetic shielding plate and method for producing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2002-09-11 EP claimed
EP-0694530-B1 Process for cross-coupling of aromatic boron compounds with aromatic halogen compounds or perfluoroalkyl sulphonates AVENTIS RES & TECH GMBH & CO (DE) 2000-08-23 EP claimed
US-5919930-A Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates HOECHST AKTIENGESELLSCHAFT (DE) 1999-07-06 US claimed
EP-0709357-A1 Method for the cross-coupling of aromatic halo compounds or perfluoroalkanesulphonates with terminal alkynes HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-01 EP claimed
EP-0694530-A2 Process for cross-coupling of aromatic boron compounds with aromatic halogen compounds of perfluoroalkyl sulphonates HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP claimed
EP-0062005-A1 Process for the manufacture of styrene and/or stilbene derivatives CIBA-GEIGY AG (CH) 1982-10-06 EP claimed
US-20260082461-A1 Organic Electroluminescent Device UDC IRELAND LTD (IE) 2026-03-19 US disclosed
EP-3927685-B1 A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD (IN) 2025-10-08 EP disclosed
US-12402218-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2025-08-26 US disclosed
CN-116283725-B Aromatic amine substituted dibenzofive-membered ring compound and application thereof 烟台显华科技集团股份有限公司 2025-06-24 CN disclosed
CN-113631536-B Fluorene derivative and use thereof 日产化学株式会社 2025-06-10 CN disclosed
EP-0102925-B1 N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREA CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0248245-A2 2-Fluoroalkenyl-phenyl-sulfonic-acid derivatives CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
EP-0129956-B1 PROCESS FOR ARYLATING UNSATURATED COMPOUNDS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-07-08 EP disclosed
US-4554360-A DIARYLIODONIUM SALT, IODOARENE, COUPLING NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-11-19 US disclosed
EP-0129956-A1 Process for arylating unsaturated compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-01-02 EP disclosed
EP-0102925-A2 N-phenylsulfonyl-N'-pyrimidinyl- and -triazinyl urea CIBA-GEIGY AG (CH) 1984-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260082461-A1 Organic Electroluminescent Device ITGAL, HAO2, EIF3L TDP1 4493/4885GLA 1142/4885MAPT 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.