Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765809 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL27075764 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL709626 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL709625 | 0.85 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3958269 | 0.84 | PIN1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL29738609 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL26697220 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL18707366 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5132454 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6563664 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074104-A1 | PROCESS FOR PREPARING 6-PHEN0XYPYRIMIDIN-4-OL DERIVATIVES IN THE PRESENCE OF A QUINUCLIDINE OR A N-METHYL PYRROLIDINE DERIVATIVE | Syngenta Limited (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008043977-A1 | PROCESS FOR PREPARING 6-PHEN0XYPYRIMIDIN-4-OL DERIVATIVES IN THE PRESENCE OF A QUINUCLIDINE OR A N-METHYL PYRROLIDINE DERIVATIVE | SYNGENTA LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |