Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827106 | 0.73 | KMT2A (0.68) | ALDH1A1LMNANPSR1MAPTHPGD | |
| SCHEMBL1918788 | 0.66 | KDM4E (0.64) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL11394109 | 0.65 | PRMT5 (0.46) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL16557465 | 0.64 | ALDH1A1 (0.76) | ALDH1A1NPSR1MAPTNPC1RAB9A | |
| SCHEMBL806658 | 0.64 | KMT2A (0.67) | ALDH1A1LMNANPSR1MAPTNPC1 | |
| SCHEMBL12827268 | 0.64 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL14947473 | 0.63 | ADRA1D (0.59) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL24169559 | 0.63 | POLB (0.63) | ALDH1A1LMNANPSR1MAPTKMT2A | |
| SCHEMBL30950617 | 0.62 | NPSR1 (0.80) | ALDH1A1LMNANPSR1MAPTHPGD | |
| SCHEMBL30292443 | 0.61 | POLB (0.48) | MAPTKMT2ASMN1; SMN2MEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |