Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265374 | 0.76 | MEN1 (0.69) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL11888649 | 0.72 | GAA (0.64) | KMT2AMEN1ALDH1A1NPSR1POLB | |
| SCHEMBL20657050 | 0.71 | KMT2A (0.76) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13652637 | 0.70 | KMT2A (0.60) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10695522 | 0.70 | KMT2A (0.60) | KMT2AMEN1POLBLMNAMAPT | |
| SCHEMBL529488 | 0.70 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL806780 | 0.70 | SMN1; SMN2 (1.00) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17340104 | 0.70 | OXTR (0.64) | KMT2AMEN1ALDH1A1NPSR1POLB | |
| SCHEMBL28101490 | 0.69 | RAB9A (0.66) | KMT2AMEN1ALDH1A1NPSR1POLB | |
| SCHEMBL24279764 | 0.69 | MMP2 (0.57) | KMT2AMEN1ALDH1A1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |