Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309422 | 0.86 | NAMPT (0.43) | MASP2NAMPTCDK8VNN1HDAC1 | |
| SCHEMBL4306839 | 0.86 | NAMPT (0.47) | MASP2NAMPTMEN1KMT2ACDK8 | |
| SCHEMBL4304420 | 0.86 | MEN1 (0.47) | MASP2NAMPTMEN1KMT2ACDK8 | |
| SCHEMBL4303439 | 0.86 | NAMPT (0.53) | MASP2NAMPTMEN1KMT2AF2 | |
| SCHEMBL4312874 | 0.84 | VNN1 (0.55) | MASP2NAMPTVNN1 | |
| SCHEMBL4309586 | 0.84 | F2 (0.45) | NAMPTMEN1KMT2ARECQLF2 | |
| SCHEMBL4305726 | 0.81 | NAMPT (0.45) | MASP2NAMPTMEN1KMT2AVNN1 | |
| SCHEMBL4308746 | 0.81 | NAMPT (0.41) | MASP2NAMPTMEN1KMT2A | |
| SCHEMBL4307976 | 0.80 | NAMPT (0.49) | MASP2NAMPTMEN1KMT2AHDAC1 | |
| SCHEMBL4309387 | 0.80 | NAMPT (0.44) | MASP2NAMPTF2PRSS1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |