Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | VNN1 | O95497 | 3/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 3/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318894 | 0.87 | MEN1 (0.45) | MEN1KMT2ATACR1POLBNAMPT | |
| SCHEMBL4306839 | 0.86 | NAMPT (0.47) | MEN1KMT2AVNN1CDK8NAMPT | |
| SCHEMBL4309422 | 0.84 | NAMPT (0.43) | VNN1CDK8NAMPT | |
| SCHEMBL4308748 | 0.84 | MASP2 (0.44) | F2MEN1KMT2AVNN1CDK8 | |
| SCHEMBL4303439 | 0.83 | NAMPT (0.53) | F2MEN1KMT2APOLBNAMPT | |
| SCHEMBL3153097 | 0.81 | F2 (0.49) | F2MEN1KMT2ACDK8CDK7 | |
| SCHEMBL4312874 | 0.81 | VNN1 (0.55) | VNN1NAMPT | |
| SCHEMBL4304420 | 0.81 | MEN1 (0.47) | MEN1KMT2APOLBCDK8NAMPT | |
| SCHEMBL4305726 | 0.80 | NAMPT (0.45) | MEN1KMT2AVNN1NAMPTPDPK1 | |
| SCHEMBL4307976 | 0.80 | NAMPT (0.49) | MEN1KMT2ANAMPTPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |